The depth of mutational agony and the exuberance of tumoral T cell ecstasy predict checkpoint salvation.

Sci Immunol

Illawarra Health and Medical Research Institute, University of Wollongong, Keiraville, Australia. Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA 02139, USA. Email:

Published: December 2018

Genomic biomarkers will help to elucidate which cancer patients will benefit from PD-1 blockade immunotherapy.

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http://dx.doi.org/10.1126/sciimmunol.aav9722	DOI Listing

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