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Assessment of Pharmacologic Ingredients in Common Over-the-Counter Sinonasal Medications.
JAMA Otolaryngol Head Neck Surg
September 2020
Department of Otorhinolaryngology, Ochsner Clinic Foundation, New Orleans, Louisiana.
Importance: Sinonasal remedies are the most frequently purchased category of over-the-counter (OTC) drugs in the United States. A variety of options for relief are available under proprietary names, although the actual number of available options may not be readily appreciated by the consumer or the clinician.
Objective: To determine the prevalence of specific ingredients in OTC sinonasal products.
The CD45dim/CD123bright/HLADRneg BAT in the Anti-histamine Drug Allergy.
Iran J Allergy Asthma Immunol
April 2020
Council for Nutritional and Environmental Science (CONEM), Mo i Rana, Norway.
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View Article and Find Full Text PDFDevelopment and validation of a generic RP-HPLC PDA method for the simultaneous separation and quantification of active ingredients in cold and cough medicines.
Biomed Chromatogr
November 2019
School of Chemistry & Physics, College of Agriculture, Engineering and Science, Westville Campus, University of KwaZulu-Natal, Durban, South Africa.
A novel generic reverse phase high performance liquid chromatography (RP-HPLC) method is developed and validated for simultaneous determination of seven pharmaceutically active ingredients, namely, acetaminophen, dextromethorphan, doxylamine, phenylephrine, guaifenesin, caffeine and aspirin. All seven ingredients were quantified in soft gel, syrup and tablet formulations of the over-the-counter US-marketed products, as per the guidelines of the International Conference on Harmonization. The separation was achieved in a 16 min run time on an Agilent Zorbax Phenyl column using a gradient method with two mobile phases.
View Article and Find Full Text PDFDoxylamine Allergy in a Pregnant Woman: Suitability of the Basophil Activation Test.
J Investig Allergol Clin Immunol
December 2018
Immunology Department, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain.
Doxylamine succinate overdose: Slurred speech and visual hallucination.
Turk J Pediatr
May 2019
Department of Pediatric Emergency, Gazi University Faculty of Medicine, Ankara, Turkey.
Derinöz-Güleryüz O. Doxylamine succinate overdose: Slurred speech and visual hallucination. Turk J Pediatr 2018; 60: 439-442.
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