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[Clinical characteristics and prognosis of children with T-lineage acute lymphoblastic leukemia: a single-center study].
Zhongguo Dang Dai Er Ke Za Zhi
December 2024
Department of Hematology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510000, China.
Objectives: To study the clinical characteristics and prognosis of T-lineage acute lymphoblastic leukemia (T-ALL) and related prognostic factors.
Methods: A retrospective analysis was conducted on the children with T-ALL who were treated with the Chinese Children's Cancer Group Acute Lymphoblastic Leukemia (CCCG-ALL) regimen in Guangzhou Women and Children's Medical Center between April 2015 and December 2022.
Results: A total of 80 children were included, with a median age of 7 years and 3 months and a male/female ratio of 6:1.
Reproductive toxicity and molecular mechanisms of benzo[a]pyrene exposure on ovary, testis, and brood pouch of sex-role-reversed seahorses (Hippocampus erectus).
Environ Pollut
December 2024
School of Fisheries, Ludong University, Yantai, 264025, China; Research and Development Center of Science, Technology and Industrialization of Seahorses, Ludong University, Yantai, 264025, China. Electronic address:
As a flagship taxa for marine ecosystems, seahorses possess a unique reproductive strategy of "male pregnancy". They are severely threatened by marine petroleum-based pollution but the molecular mechanism involved remains unclear. We evaluated the toxic effects and mechanisms of sub-acute exposure to benzo[a]pyrene (BaP), a representative polycyclic aromatic hydrocarbon (PAH), at three environmental related dosages (0.
View Article and Find Full Text PDFAcute Abdominal Pain in Children: Evaluation and Management.
Am Fam Physician
December 2024
Indiana University School of Medicine, Indianapolis.
Acute abdominal pain in children is a common presentation in the clinic and emergency department settings and accounts for up to 10% of childhood emergency department visits. Determining the appropriate disposition of abdominal pain in children can be challenging. The differential diagnosis of acute abdominal pain, including gastroenteritis, constipation, urinary tract infection, acute appendicitis, tubo-ovarian abscess, testicular torsion, and volvulus, and the diagnostic approach vary by age.
View Article and Find Full Text PDFIntrauterine Testicular Torsion: Two Prenatally Diagnosed Cases and Review of the Literature.
J Clin Ultrasound
December 2024
Department of Obstetrics and Neonatology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), AUSL Reggio Emilia, Reggio Emilia, Italy.
The third-trimester ultrasound diagnosis in two fetuses with isolated testicular torsion is described. Pregnancy courses were uneventful and routine second-trimester scans had shown no structural anomalies. Antenatal ultrasound performed at 32 + 3 and 33 + 0 weeks' gestation showed signs consistent with the diagnosis of isolated left spermatic cord torsion in both cases (absent flow across the testicular artery, hyperechogenic small rounded mass in the hemiscrotum representing the twisted testes, and hydrocele).
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