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[Pseudohiponatremia secondary to hypertriglyceridemia during the treatment of lymphoblastic lymphoma with corticoids and L-asparaginase].
Andes Pediatr
August 2024
Hemato-Oncología Infantil, Universidad Austral de Chile, Valdivia, Chile.
Unlabelled: L-asparaginase (L-asp) is an antineoplastic drug used in Leukemia and Lymphoma treatment protocols. Alterations in lipid metabolism have been reported in 10-50% of children treated with L-Asp.
Objective: To report an unusual complication of lipid metabolism associated with the use of L-Asp.
Long-Term Persistence of Inappropriate Antidiuretic Hormone Secretion Following Minor Head Injury.
Eur J Case Rep Intern Med
November 2024
Department of Internal Medicine, Iris Hospitals South (Molière), Brussels, Belgium.
Unlabelled: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of euvolemic hyponatremia, resulting from non-osmotic release of antidiuretic hormone (ADH). SIADH is frequently associated with neurological conditions, including traumatic brain injury (TBI). TBI-associated SIADH usually develops within days to weeks and resolves within a few weeks.
View Article and Find Full Text PDFDelayed Emergence of Isolated Secondary Adrenal Insufficiency: A Case Report.
Cureus
October 2024
Family Medicine, Baptist Health of South Florida, Miami, USA.
Article Synopsis
- Secondary adrenal insufficiency (SAI) is a rare condition caused by a deficiency in the adrenocorticotropic hormone (ACTH) from the pituitary gland, leading to symptoms like chronic low sodium levels (hyponatremia), and can present a diagnostic challenge, particularly when there are no identifiable triggers.
- An 80-year-old woman with a history of multiple health issues was diagnosed with isolated adrenal insufficiency after presenting with weakness and fatigue, leading to complications that required specific treatments including corticosteroids.
- This case highlights the importance of recognizing atypical presentations of adrenal insufficiency, as well as the effectiveness of corticosteroid replacement therapy in resolving symptoms and normalizing sodium levels.
Complex glycerol kinase deficiency: A case report.
Arch Argent Pediatr
November 2024
Clinical Pediatric Residency, Intermediate-Medium Care Unit III, Hospital Público Materno Infantil, Salta, Argentina.
Glycerol kinase deficiency is a rare X-linked genetic disorder, which may be associated with adrenal hypoplasia congenita and Duchenne muscular dystrophy. Here we describe a complex pediatric case of adrenal insufficiency with persistent hyponatremia and hyperkalemia despite an adequate management with corticosteroids, hypertriglyceridemia since birth, and chronic malnutrition in nutritional recovery. No cases have been reported in the Argentine literature, which increases the relevance of this case in pediatric clinical practice due to its unusual presentation.
View Article and Find Full Text PDFExercise-Associated Hyponatremic Encephalopathy, Rhabdomyolysis, and Acute Kidney Injury While Hiking in the Grand Canyon.
Wilderness Environ Med
December 2024
University of Arizona College of Medicine, Phoenix, AZ, USA.
Article Synopsis
- A 41-year-old male hiker experienced a serious medical emergency after consuming too much water while hiking in the Grand Canyon during hot weather, leading to multiple health issues.
- He suffered from exercise-associated hyponatremic encephalopathy (EAHE), exertional rhabdomyolysis (ER), and acute kidney injury (AKI), which resulted in severe pain, disorientation, and a grand mal seizure during helicopter evacuation.
- The case highlights the dangers of excessive water intake, potential complications from strenuous exercise, and the need for prompt treatment of life-threatening conditions like EAHE and compartment syndromes.
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