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Infections and Antibiotherapy: Results of Four Years of Observation in a Romanian Tertiary Hospital.
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Department of Epidemiology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
infection (CDI) is one of the main causes of morbidity associated with antibiotic use, producing both healthcare-associated infections and community infections. This study aims to describe the epidemiological characteristics, the clinical outcomes, previous antibiotic exposure, and other risk factors of hospitalized patients with CDI in a tertiary infectious disease hospital in Bucharest, Romania. We performed a descriptive analysis based on four-year surveillance data, collected in a tertiary infectious disease hospital in Bucharest, Romania.
View Article and Find Full Text PDFThe First Case of Endocarditis in Italy: Case Presentation and Systematic Literature Review.
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Infectious and Tropical Diseases Unit, Padua University Hospital, 35128 Padua, Italy.
Almost 25 years have now passed since the first identification of (). It can cause infections both in immunocompetent and immunocompromised hosts. However, it has been rarely described as an aetiology of infectious endocarditis.
View Article and Find Full Text PDFESBL- and pAmpC-producing Enterobacterales from Swedish dogs and cats 2017-2021: a retrospective study.
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Department of Animal Health and Antibiotic Strategies, Swedish Veterinary Agency, Uppsala, Sweden.
Background: Antibiotic resistant bacteria are a threat to both human and animal health. Of special concern are resistance mechanisms that are transmissible between bacteria, such as extended-spectrum beta-lactamases (ESBL) and plasmid-mediated AmpC (pAmpC). ESBL/AmpC resistance is also of importance as it confers resistance to beta-lactam antibiotics including third generation cephalosporins.
View Article and Find Full Text PDFPrevalence and Antimicrobial Resistance Trends among Lower Respiratory Tract Pathogens in Crete, Greece, 2017-2022.
Infect Chemother
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Department of Clinical Microbiology and Microbial Pathogenesis, University Hospital of Heraklion, Crete, Greece.
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View Article and Find Full Text PDFAdditional benefits of combined ceftriaxone and adipose-derived mesenchymal stem cells on revamping the outcomes in rodent after acute spinal infection.
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Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Dapi Rd. Niaosung Dist, Kaohsiung City, 83301, Taiwan.
Article Synopsis
- The study examined the effects of ceftriaxone and adipose-derived mesenchymal stem cells (ADMSCs) on protecting the spinal cord from acute spinal infection (ASI) in rats.
- Results showed that the combination treatment of ceftriaxone and ADMSCs led to significantly lower inflammatory markers and bacterial counts compared to the individual treatments, indicating better inflammation control and tissue preservation.
- By day 28, the combination therapy demonstrated superior results in protecting vertebral bone and spinal cord integrity compared to each treatment alone, suggesting a potential therapeutic strategy for ASI.
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