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http://dx.doi.org/10.1016/j.drugpo.2018.11.008 | DOI Listing |
Prehosp Disaster Med
January 2025
Department of Emergency Medicine, Summa Health System, Northeast Ohio Medical University, Akron, OhioUSA.
Background: Over 2.7 million people have an opioid use disorder (OUD). Opioid-related deaths have steadily increased over the last decade.
View Article and Find Full Text PDFPublic Health
January 2025
Department of Public Health Policy and Management, School of Global Public Health, New York University, 726 Broadway, New York, NY, 10012, United States.
Objective: To assess the substance use disorder (SUD) prevention and response activities that county governments in New York advertise.
Study Design: Cross-sectional study.
Methods: We coded websites of county public health, mental health, emergency, and social service departments to identify whether any government agency provided information about ten evidence-based SUD services.
J Urban Health
January 2025
Department of Population Health Sciences, Weill Cornell Medical College, New York, NY, USA.
From 2014 to 2017, the drug overdose death rate per 100,000 in New York City (NYC) increased by 81%, with 57% of overdoses in 2017 involving the opioid fentanyl. In response, overdose education and naloxone dispensing (OEND) efforts were expanded in NYC, informed by neighborhood-level and population-level opioid overdose fatality rates. We describe the demographic and geographical distribution of naloxone by NYC opioid overdose prevention programs (OOPPs; the primary distributor of naloxone to laypersons in NYC) as OEND was expanded in NYC.
View Article and Find Full Text PDFIntroduction: Mu-opioid receptors (MORs) are G-coupled protein receptors with a high affinity for both endogenous and exogenous opioids. MORs are widely expressed in the central nervous system (CNS), peripheral organs, and the immune system. They mediate pain and reward and have been implicated in the pathophysiology of opioid, cocaine, and other substance use disorders.
View Article and Find Full Text PDFPrehosp Emerg Care
January 2025
Department of Emergency Medicine, MetroHealth Medical Center, Cleveland, Ohio.
Objectives: Opioid-associated fatal and non-fatal overdose rates continue to rise. Prehospital overdose education and naloxone distribution (OEND) programs are attractive harm-reduction strategies, as patients who are not transported by EMS after receiving naloxone have limited access to other interventions. This narrative summary describes our experiences with prehospital implementation of evidence-based OEND practices across Ohio as part of the HEALing Communities Study (HCS).
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