The history of chronic dialysis in the United States highlights the impact nephrology leaders have on improving kidney disease care. Belding Scribner and his Seattle team transformed end-stage renal disease from a fatal illness to a treatable condition with use of the first successful Scribner shunt in 1960. Advances in dialysis machines emerged from Les Babb and Richard Drake finding ways to treat more patients. Innovative nephrology leaders foster incremental change leading to the technically complex, life-sustaining treatments that are widely available to end-stage renal disease patients today. The Nephrology Oral History Project consists of interviews with patient, nurse, and nephrologist pioneers who have witnessed and contributed to these advancements in kidney disease care. This article includes Nephrology Oral History Project excerpts illustrating leadership contributions to dialysis machines, peritoneal dialysis catheters, and treatment best practices. In addition to individual contributions, improvements in treatment also come from patient and provider organizations leading the way and collectively advocating for change. Nephrology leaders continue to play a crucial role in improving dialysis outcomes and quality of life.
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http://dx.doi.org/10.1053/j.ackd.2018.08.016 | DOI Listing |
Vaccines (Basel)
December 2024
Centre for Immuno-Oncology, University of Oxford, Oxford OX3 7DQ, UK.
Safeguarding patients from emerging infectious diseases demands strategies that prioritise patient well-being and protection. Immunobridging is an established trial methodology which has been increasingly employed to ensure patient protection and provide clinicians with swift access to vaccines. It uses immunological markers to infer the effectiveness of a new drug through a surrogate measure of efficacy.
View Article and Find Full Text PDFBMC Public Health
January 2025
The First Clinical Medical College of Fujian Medical University, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Background: Cardiovascular-kidney-metabolic (CKM) syndrome and systemic inflammation significantly contribute to mortality. However, the joint associations of CKM stages and systemic inflammation with all-cause and cardiovascular disease (CVD) mortality remain unclear. This study aimed to evaluate the independent and joint associations of CKM stages and systemic inflammation with all-cause and CVD mortality in a representative cohort of United States adults.
View Article and Find Full Text PDFMedEdPORTAL
December 2024
Dean, Universidad Central Del Caribe, School of Medicine; Executive Director, Latino Medical Student Association.
Introduction: In light of the lack of diversity in academic medicine leadership, diversity-related, student-led national medical organizations (NMOs) provide a space for solace and reprieve among common peers while providing an opportunity to develop leadership competencies in a supportive environment. Despite the impact NMOs have had on cultivating generations of leaders in medicine, trainees may not identify opportunities for leadership development that are transferable to future careers in academic medicine.
Methods: We designed and implemented a dynamic 60-minute workshop with an interactive PowerPoint presentation, author-owned video testimonials (from past student leaders of NMOs), two case presentations, and reflection exercises.
Mol Med
December 2024
Department of Nephrology, First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan Province, China.
Background: Diabetes often causes diabetic nephropathy (DN), a serious long-term complication. It is characterized by chronic proteinuria, hypertension, and kidney function decline, can progress to end-stage renal disease, lowering patients' quality of life and lifespan. Inflammation and apoptosis are key to DN development.
View Article and Find Full Text PDFBackground: Cardiovascular diseases are the leaders in morbidity and mortality worldwide. The most common cause of emergency hospitalization of cardiac patients is acute coronary syndrome, represented by acute forms of coronary heart disease: unstable angina and myocardial infarction. Among the young population (18-44 years old, according to WHO), in contrast to the older cohort, there has been a significant increase in cardiovascular morbidity over the last two decades.
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