AI Article Synopsis
- Neonicotinoid insecticides show varying levels of toxicity to honey bees, with imidacloprid being significantly more toxic than thiacloprid and acetamiprid.
- The study measured how honey bees uptake, metabolize, and excrete these chemicals using advanced techniques.
- Findings indicate that imidacloprid penetrates bee cuticles faster and maintains higher concentrations in the body, contributing to its increased toxicity.
Article Abstract
Neonicotinoid insecticides differ in their acute contact toxicity to honey bees. We investigated the uptake, metabolic fate, and excretion of imidacloprid and two much less toxic chemotypes, thiacloprid and acetamiprid, upon contact exposure in honey bees because ADME data for this mode of entry are lacking. Pharmacokinetic parameters were analyzed by tracking a C-label and by HPLC coupled to ESI-MS. Imidacloprid penetrates the honey bee cuticle much faster and more readily compared to thiacloprid and acetamiprid, thus revealing a pharmacokinetic component, i.e., faster penetration and higher steady-state internal body concentrations, contributing to its higher acute contact toxicity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.chemrestox.8b00315 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Portable Self-Powered/Colorimetric Dual-Mode Sensing Platform Based on Multifunctional Bioconjugates for Precise On-Site Detection of Acetamiprid.
Anal Chem
January 2025
College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, P. R. China.
Neonicotinoid insecticides have been widely applied in modern agriculture to improve crop productivity, but their residues have adverse impacts on the environment and human health. Hence, to address these issues, a portable self-powered/colorimetric dual-mode sensing platform was developed for the simple, rapid, precise, and sensitive on-site detection of acetamiprid (ATM) residues in vegetables. In this case, a multifunctional bioconjugate with specific recognition capability, excellent enzyme-like activity, and loading capacity is the key to the sensing design.
View Article and Find Full Text PDFCross-Resistance to Pyrethroids and Neonicotinoids in Malaria Vectors from Vegetable Farms in the Northern Benin.
Trop Med Infect Dis
December 2024
Agroecohealth Unit, International Institute of Tropical Agriculture (IITA), 08 Tri-Postal, Cotonou P.O. Box 0932, Benin.
Agricultural pesticides may play a crucial role in the selection of resistance in field populations of mosquito vectors. This study aimed to determine the susceptibility level of s.l.
View Article and Find Full Text PDFResidue behavior of imidacloprid FS formulation in peanut cultivation system in china and its dietary and ecological risk assessment.
Environ Geochem Health
December 2024
State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, No.2, West Yuan-Ming-Yuan Road, Beijing, 100193, China.
Imidacloprid, a key neonicotinoid insecticide for pest control, is widely used in various crops, including peanuts. This study aimed to fill research gaps by analysing the residue behaviour of imidacloprid in peanut fields treated with flowable concentrate for seed treatment (FS) formulations while assessing potential risks to human health and ecosystems. A validated analytical method, using QuEChERS separation and UPLC-MS/MS detection, reliably quantified imidacloprid residues in peanuts and soil.
View Article and Find Full Text PDFAquatic occurrence, fate and potential ecotoxicity of insecticide and fungicide residues originating from a biofuels production facility using pesticide-treated seeds.
J Hazard Mater
December 2024
Civil & Environmental Engineering, University of Nebraska Lincoln, Lincoln, NE 68588, USA.
Little is known about the potential impact of point source contamination from seed treatment pesticide residues and degradation products in waste products in treated seed. The presence of these pesticides and their degradation products in the environment has been associated with toxic effects on non-target organisms including bees, aquatic organisms and humans. In this study, we investigated the occurrence of twenty-two pesticide residues and their degradation products in two streams receiving runoff from land-applied wet cake, applied and spilled wastewater originating at a biofuels production facility using pesticide-treated seed as a feedstock.
View Article and Find Full Text PDFEmbryonic exposure to acetamiprid insecticide induces CD68-positive microglia and Purkinje cell arrangement abnormalities in the cerebellum of neonatal rats.
Toxicol Appl Pharmacol
December 2024
Department of Applied Chemistry and Life Sciences, Graduate School of Engineering, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan; Center for Diversity and Inclusion, Toyohashi University of Technology, Toyohashi, Aichi, 441-8580, Japan. Electronic address:
Concerns have been raised regarding acetamiprid (ACE), a neonicotinoid insecticide, due to its potential neurodevelopmental toxicity. ACE, which is structurally similar to nicotine, acts as an agonist of nicotinic acetylcholine receptors (nAChRs) and resists degradation by acetylcholinesterase. Furthermore, ACE has been reported to disrupt neuronal transmission and induce developmental neurotoxicity and ataxia in animal models.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!