Background: The majority of small-scale gold miners worldwide, including those in Mozambique, use mercury to extract gold. Over the last fifty years, gold production from small-scale mining has been accelerating and consequently the amount of mercury released to the environment has increased dramatically, causing major global health problems. In 2018, a team from the Danish non-governmental organization Diálogos introduced the mercury-free gold extraction method in the Cabo Delgado province in Mozambique in the villages of Waqueia and Nanlia.
Objectives: The objective of this project was to teach local miners this method to reduce mercury pollution. An additional objective was to compare the local gold extraction method and the mercury-free gold extraction method in terms of gold recovery. The hypothesis was that the level of gold recovery would be higher with the mercury-free method compared to the locally used amalgamation method.
Materials And Methods: An experimental study comparing the two gold extraction methods was carried out where local miners processed gold-bearing ore using their standard procedures with the amalgamation method and the Diálogos team processed an equivalent amount of gold-bearing ore with the mercury-free gold extraction method. The tests were carried out once at each mining site.
Results: Under even circumstances in a controlled setting, the mercury-free method yielded up to 78% more gold than the amalgamation method normally used by the miners.
Conclusions: The strengths of the mercury-free gold extraction method include low costs, higher gold yield, benign environmental impact, legality and needed chemicals are more readily available compared with the amalgamation method. However, the mercury-free method may be more time consuming than the amalgamation method, especially for beginners. Borax is typically available in developed urban areas, as it is commonly used in the welding industry and by jewelers, but can be hard to find in more remote villages.
Competing Interests: The authors declare no competing financial interests.
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http://dx.doi.org/10.5696/2156-9614-8.19.180909 | DOI Listing |
Background: Changes in speech and language functions have shown to be early symptoms of AD pathology. Recent developments in automatic speech and language processing have opened avenues for objective assessments of these changes. The primary objective of this study is to explore whether speech and language markers extracted from cognitive testing conducted during an automated phone call differ according to underlying AD pathology as measured in cerebrospinal fluid (CSF) in preclinical or early stage individuals.
View Article and Find Full Text PDFBackground: Speech and language impairments are associated with cognitive decline in neurodegenerative dementias, particularly Alzheimer's Disease (AD), where subtle speech changes may precede clinical dementia onset. As clinical trials prioritize early identification for disease-modifying treatments, digital biomarkers for timely screening become imperative. Digital speech-based biomarkers can be employed for screening populations at the earliest AD stages.
View Article and Find Full Text PDFLab Chip
January 2025
School of Biomedical Engineering, Tsinghua University, Haidian District, Beijing 100084, China.
Rapid and accurate molecular diagnostics are crucial for preventing the global spread of emerging infectious diseases. However, the current gold standard for nucleic acid detection, reverse transcription polymerase chain reaction (RT-PCR), relies heavily on traditional magnetic beads or silica membranes for nucleic acid extraction, resulting in several limitations, including time-consuming processes, the need for trained personnel, and complex equipment. Therefore, there is an urgent need for fully integrated nucleic acid detection technologies that are simple to operate, rapid, and highly sensitive to meet unmet clinical needs.
View Article and Find Full Text PDFBehav Res Methods
January 2025
Neuroscience of Perception and Action Lab, Italian Institute of Technology (IIT), Viale Regina Elena 291, 00161, Rome, Italy.
Estimating how the human body moves in space and time-body kinematics-has important applications for industry, healthcare, and several research fields. Gold-standard methodologies capturing body kinematics are expensive and impractical for naturalistic recordings as they rely on infrared-reflective wearables and bulky instrumentation. To overcome these limitations, several algorithms have been developed to extract body kinematics from plain video recordings.
View Article and Find Full Text PDFTalanta
December 2024
Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350108, China. Electronic address:
The flap endonuclease 1 (FEN1) plays a key role in DNA replication and repair, its aberrant expression is associated with tumor development, so it has been recognized as a promising biomarker for a variety of cancers. Here, a novel "turn on" mode gold nanocube-enhanced surface-enhanced Raman scattering (SERS) biosensor was constructed by combining a heated Au electrode (HAuE), exonuclease III (Exo III)-assisted cycle amplification, and gold nanocube (AuNC)-based SERS enhancement to achieve highly sensitive detection of FEN1 activity. The SERS tag was prepared using the Raman reporter modified on the AuNC surface, and the high electromagnetic field provided by the sharp geometric feature of AuNC greatly enhanced the SERS signal.
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