Objective: To win a Christmas hamper. We also devised a study of our most festive seasonal poisoning, to demonstrate how hard we are working while everyone else is partying.
Design: Retrospective analysis of the New South Wales Poisons Information Centre database, which we searched for exposures to the substance code "Cyalume light sticks/glow toys" from 1 July 2013 to 30 June 2017.
Setting: A dimly lit basement with a constantly ringing phone. At the other end of the phone was a highly anxious parent and a luminescent child.
Main Outcome Measures: Number of glow stick exposures, route of exposures, patient demographics and seasonal trends in exposures.
Results: There were 2918 glow stick exposures over the 4-year study period. The vast majority of exposures (94%) were in children aged 14 years and younger. Medical complications were very rare. Glow stick exposures were 4.38 times more likely in December (95% CI, 3.02-6.35; P < 0.001). Statistically significant increases were also observed in October, November, January, February and March. Glow stick exposures were 4.20 times more likely during the holiday period of 1 December to 7 January (95% CI, 3.42-5.15; P < 0.001), 2.52 times more likely over summer (95% CI, 2.12-3.00; P < 0.001), and 1.77 times more likely during school holidays (95% CI, 1.47-2.13; P < 0.001).
Conclusions: This epidemic of poisoning is perhaps due to mass seasonal synaesthesia. The lack of any significant adverse consequences highlights the contribution that 50 years of injury prevention has made to everyone having a Merry Christmas and a Happy New Year.
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http://dx.doi.org/10.5694/mja18.01032 | DOI Listing |
Acc Chem Res
May 2024
William A. Brookshire Department of Chemical and Biomolecular Engineering, University of Houston, Houston, Texas 77004, United States.
The COVID-19 pandemic further demonstrated the need for usable, reliable, and cost-effective point-of-care diagnostics that can be broadly deployed, ideally for self-testing at home. Antigen tests using more-detectable reporter labels (usually at the cost of reader complexity) achieve better diagnostic sensitivity, supporting the value of higher-analytical-sensitivity reporter technologies in lateral flow.We developed a new approach to simple, inexpensive lateral flow assays (LFAs) of great sensitivity, based on the glow stick peroxyoxalate chemistry widely used in emergency settings and in children's toys.
View Article and Find Full Text PDFAnalyst
November 2023
Department of Chemistry, Prairie View A&M University, Prairie View, Texas, USA.
Glow enzyme-linked immunosorbent assay (glow ELISA) uses inexpensive and shelf-stable glow stick reagents to chemically excite fluorescent reporters, obviating the need for excitation light sources, filters, and complex optics. It achieves excellent limits of detection while offering portability and equipment cost comparable to lateral flow immunoassays.
View Article and Find Full Text PDFEye Contact Lens
December 2022
Department of Contact Lens, Sankara Nethralaya, Unit of Medical Research Foundation, Chennai, India.
The purpose of this case report was to represent the clinical expertise in managing with a patient with visible red fundal reflex on flash photography and its management with a soft prosthetic contact lens (PCL). This unique case report discussed a 31-year-old man complaining of visible red reflex in right eye while taking photographs with flashlight. Ocular history revealed that he is status post intraocular lens implantation and strabismus surgery followed by a nonpenetrating injury with a stick in the right eye 20 years back.
View Article and Find Full Text PDFJ Org Chem
September 2021
Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, 05508-000 São Paulo, SP, Brazil.
Peroxyoxalate chemiluminescence is used in self-contained light sources, such as glow sticks, where oxidation of aromatic oxalate esters produces a high-energy intermediate (HEI) that excites fluorescence dyes via electron transfer chemistry, mimicking bioluminescence for efficient chemical energy-to-light conversion. The identity of the HEI and reasons for the efficiency of the peroxyoxalate reaction remain elusive. We present here unequivocal proof that the HEI of the peroxyoxalate system is a cyclic peroxidic carbon dioxide dimer, namely, 1,2-dioxetanedione.
View Article and Find Full Text PDFMed J Aust
December 2018
University of Sydney, Sydney, NSW.
Objective: To win a Christmas hamper. We also devised a study of our most festive seasonal poisoning, to demonstrate how hard we are working while everyone else is partying.
Design: Retrospective analysis of the New South Wales Poisons Information Centre database, which we searched for exposures to the substance code "Cyalume light sticks/glow toys" from 1 July 2013 to 30 June 2017.
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