AI Article Synopsis
- - The study analyzes cancer drug trials listed on ClinicalTrials.gov to see how trial designs change over time.
- - It looks at both later updates to the trials and published journal reports to identify these changes and the reasons behind them.
- - The research also evaluates how transparent these modifications are in the reporting process.
Article Abstract
This study matches entries in ClinicalTrials.gov for cancer drug trials at initiation of the trial with later entries and with journal reports of the trials to assess modifications in trial design, external factors associated with such modifications, and transparency in reporting them.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440244 | PMC |
| http://dx.doi.org/10.1001/jamaoncol.2018.5877 | DOI Listing |
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