We report three chronic asymptomatic HBsAg carrier mothers. We studied their placentas via application of the immunohistochemical method to identify HBsAg by peroxidase-antiperoxidase techniques. All three placental specimens showed a positive HBsAg reaction. Due to the strong cytoplasmatic reactivity of the cytotypes, we deduced their active participation in the infection, proving that virosis occurs via transplacental circulation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0002-9378(88)80149-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Clinical characteristics and genetic analysis of two children with Multiple mitochondrial dysfunction syndrome due to variants of IBA57 gene].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
January 2025
Department of Pediatric Neurorehabilitation, Zhuhai Maternal and Child Health Care Hospital, Zhuhai, Guangdong 519000, China.
Objective: To investigate the clinical features and genetic variants associated with Multiple mitochondrial dysfunction syndrome (MMDS) type 3 in two children.
Methods: Two children diagnosed with MMDS type 3 at Zhuhai Maternal and Child Health Care Hospital in January 2021 were selected for this study. A retrospective analysis of their clinical data was carried out.
Glanzmann Thrombasthenia in a Newborn Due to a Rare Homozygous Missense Mutation.
Cureus
December 2024
Obstetrics and Gynecology, Latifa Hospital, Dubai, ARE.
Glanzmann thrombasthenia (GT) is an autosomal recessive platelet functional bleeding disorder caused by mutations in the ITGA2B or ITGB3 genes, often presenting as mucocutaneous bleeding. GT typically presents in infancy, but this study reports a rare case of neonatal presentation in a female infant born to consanguineous parents. The mother, a 27-year-old woman with a family history of GT, presented at 36 weeks gestation for an elective cesarean due to a breech presentation.
View Article and Find Full Text PDFDeterminants of Preventive Health Behavior for Hepatitis B in Pregnant Women: A Cross-Sectional Study.
J Nurs Res
January 2025
School of Nursing, National Tainan Junior College of Nursing, Tainan, Taiwan.
Background: Vertical transmission from mother to child during the perinatal period is a key route of hepatitis B infection. The infection rate among children of mothers who are hepatitis B carriers is high.
Purpose: This study was designed to investigate the hepatitis-B-related preventive health behavior of pregnant women and related factors.
Prospective study of peripartum group B streptococcus colonization in Japanese mothers and neonates.
Epidemiol Infect
January 2025
Department of Obstetrics and Gynecology, Juntendo University Urayasu Hospital, Chiba, Japan.
Article Synopsis
- Group B streptococcus (GBS) is a significant cause of infections in neonates and pregnant women, with Japan implementing guidelines for screening and antibiotic use, yet infections have not decreased significantly.
- Approximately 15% of pregnant women lack GBS screening, and issues like intermittent colonization lead to early-onset disease; current preventative measures don't address increasing cases of late-onset disease.
- This study found that using polymerase chain reaction for GBS detection was more effective than culture methods, highlighted the risk of horizontal transmission, and emphasized the need for better diagnostic tools and potential maternal vaccination for prevention.
Sweat chloride reflects CFTR function and correlates with clinical outcomes following CFTR modulator treatment.
J Cyst Fibros
January 2025
Cystic Fibrosis Therapeutics Development Network Coordinating Center, Seattle Children's Hospital, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Department of Biostatistics, University of Washington, Seattle, WA, USA.
Background: Highly effective CFTR modulators improve CFTR function and lead to dramatic improvements in health outcomes in many people with cystic fibrosis (pwCF). The relationship between measures of CFTR function, such as sweat chloride concentration, and clinical outcomes in pwCF treated with CFTR modulators is poorly defined. We conducted analyses to better understand the relationships between sweat chloride and CFTR function in vitro, and between sweat chloride and clinical outcomes following CFTR modulator treatment.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!