AI Article Synopsis
- A new alkaloid, -L-rhamnopyranosyl-(1→6)--D-glucopyranosyl 6-methoxy-3-indolecarbonate, was discovered along with other known alkaloids, an aromatic acid, and saponins from the roots of a specific plant.
- The structures of these compounds were determined using NMR spectroscopy and acid hydrolysis techniques.
- The -butanol extract showed strong anti-inflammatory effects in mice, reducing ear swelling by 48.7% at a dose of 800 mg/kg, while two specific compounds showed even higher inhibition rates of 50.9% and 54.7% at 200 mg/kg.
Article Abstract
One new indole-type alkaloid, -L-rhamnopyranosyl-(1→6)--D- glucopyranosyl 6-methoxy-3-indolecarbonate (), together with three known alkaloids (-), one aromatic acid () and five known saponins (-), was isolated from the roots of . Their structures were established by NMR spectroscopic analysis and acid hydrolysis. In anti-inflammatory activity, -butanol extract was found to be potent against ear edema in mice, with inhibition rate of 48.7% at a dose of 800 mg/kg. Furthermore, compounds and obtained from the -butanol extract exhibited significant anti-inflammatory activities with inhibition rates of 50.9% and 54.7% at a dose of 200 mg/kg.
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| http://dx.doi.org/10.1080/14786419.2018.1510396 | DOI Listing |
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