Cp*Co(III)-catalyzed synthesis of cyclopenta[ b]carbazoles from 1-(pyridin-2-yl)-indoles and diynes is developed. This reaction involves dual C-H activation of indoles and domino cyclizations with diynes and has excellent regioselectivity, high efficiency, a broad substrate scope, and tolerance for various functional groups. A series of cyclopenta[ b]carbazole molecular scaffolds are obtained in good to excellent yields.
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| http://dx.doi.org/10.1021/acs.orglett.8b03438 | DOI Listing |
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