[THE LOCAL REGISTRY DATA ON MYOCARDIAL INFARCTION IN WOMEN: THE RISK FACTOR ANALYSIS, CLINICAL CHARACTERISTICS AND SURVIVAL].

The clinical experience implies poor prognosis in women with myocardial infarction (MI). We performed a retrospective cohort study of 1395 patients - 987 (70,75%) men and 408 (29,25%) women) aged of 64,63±11,43 years with myocardial infarction and comorbidity hospitalized between 2010-2016. This study shows an increase of mortality in women with myocardial infarction during the last 4 years from 23,1% to 34,2%. We observed more frequent cases of non-STEMI (p=0,014) and recurrent myocardial infarction in females compared with males (р<0,0001). Arterial hypertension with elevated diastolic pressure was more common women than in men (86,4% vs 68,7%, p=0,0001). Being overweight (p<0,0001), abdominal obesity (p=0,019), hypercholesterolemia, elevated low-density lipoprotein (p=0,005) were more common in females than in males. Type 2 diabetes mellitus was more frequent in women (32,6% compared with men 20,1%), the duration of the disease was also longer in females 10,3±0,8 years vs 7,3±0,5 years in men. Thyroid problems were observed more often in male (р<0,0001). Gastrointestinal ulcer was more common in men - 10,6% vs 6,6% compared with woman, p=0,019, while the bile duct diseases were more frequent in women - 8,3% vs 3,9 % compared with men, p=0,003. The mortality rate in acute myocardial infarction was 1.5-fold more frequent in women and due to age, heart rate, oxygen saturation at first day of myocardial infarction, NYHA functional class, left ventricular end-diastolic dimension index. The survival analyses after myocardial infarction was performed with the Kaplan-Meier method. It showed higher mortality level in females (χ2=26,73; р<0,0001).