One, no-one and a hundred thousand brains: J.C. Eccles, J.Z. Young and the establishment of the neurosciences (1930s-1960s).

Contemporary neurosciences have grown beyond the limits of a natural science. To its most vocal advocates, the study of the human brain can provide nothing short of the basis for a new science of man-the link between the "natural" and "human" sciences-as a simple consequence of the growing mass of facts relating to this most marvelous organ, accumulated in the last four decades. This straightforward picture of the growing import of the neurosciences simplifies and obscures the myriad different interpretations and images of "the brain" that have inspired the development of the neurosciences. Among them, this chapter will consider two deeply contrasting early images of the brain: the cellular-physiological brain proposed since the 1950s by John Carew Eccles, and the model-"whole" brain championed by John Zachary Young. Eccles' program was focused on the vertebrate synapse, and Young's on the whole brain of an "advanced" invertebrate (the octopus). The former was the programmatic extension of a long neurophysiological tradition, and the latter an outspoken attempt at providing a revolutionary model for the organization of an unprecedented research effort. One underscored continuity and scientific "soundness," and the other promised rupture and new, imaginative solutions to age-old problems. Nevertheless, they have been later lumped together into a single, marvelous and progressive history, or mythology, of the Science of the Brain. This chapter will show how the organizing principle of these two opposed (if almost equally successful) research efforts was not the foggy, ever-changing image of an experimental brain-in-becoming, but the clear, fixed horizon of a promised brain.