FoxP1 "Tspans" Quiescence and Activation of Mammary Stem Cells.

Dev Cell

Human Biology and Public Health Sciences Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Electronic address:

Published: December 2018

Stem cells can enter a reversible cell-cycle arrest state termed quiescence. In this issue of Developmental Cell, Fu et al. report that the transcription factor FoxP1 is necessary for postnatal mammary gland development and relieves Tspan8-dependent quiescence in basal mammary stem cells.

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http://dx.doi.org/10.1016/j.devcel.2018.11.017DOI Listing

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