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Multiple myeloma-associated non-crystalline proximal tubulopathy and crystalline cast nephropathy: Biochemical and structural features of disease-causing monoclonal kappa light chains.
FASEB J
January 2025
Department of Hematology, Nephrology, and Rheumatology, Graduate School of Medicine, Akita University, Akita, Japan.
Various tubular diseases in patients with multiple myeloma (MM) are caused by monoclonal immunoglobulin light chains (LCs). However, the physicochemical characteristics of the disease-causing LCs contributing to the onset of MM-associated tubular diseases remain unclear. We herein report a rare case of MM-associated combined tubulopathies: non-crystalline light chain proximal tubulopathy (LCPT) and crystalline light chain cast nephropathy (LCCN).
View Article and Find Full Text PDFComparison between Micro-(4.85Fr) and Ultramini-(<15Fr) percutaneous nephrolithotomy for the treatment of 10-20 mm kidney stones in preschool children.
J Pediatr Urol
December 2024
Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China; Institute of Urology, Beijing Municipal Health Commission, Beijing, 100050, China. Electronic address:
Introduction: The incidence of kidney stones in children has steadily increased in recent years. Miniaturized percutaneous nephrolithotomy (PCNL) techniques, such as micro-PCNL(4.85Fr) and ultramini-PCNL(<15Fr), have become increasingly prevalent in pediatric kidney stone treatment due to their high stone clearance rate and low complication rate.
View Article and Find Full Text PDFLesion Topography and Clinical Features Associated With Respiratory Failure in Patients With Medullary Infarction.
Brain Behav
January 2025
Department of Neurology, Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Huanhu Hospital, Tianjin Medical University, Tianjin, China.
Background: Respirator failure (RF) is a severe malignant complication in both lateral medullary infarction (LMI) and medial medullary infarction (MMI) patients. However, the differences in clinical and radiological manifestations associated with RF between patients with LMI and MMI have not been fully elucidated.
Methods: A total of 435 consecutive patients with MI within 7 days of onset in our institute were retrospectively enrolled from January 2017 to January 2024.
Characterizing the urobiome and associated metabolic profiles during acute rejection in renal transplant patients: A pilot study.
Transpl Immunol
January 2025
Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada. Electronic address:
Characteristic alterations in the urinary microbiome, or urobiome, are associated with renal transplant pathology. To date, there has been no direct study of the urobiome during acute allograft rejection. The goal of this study was to determine if unique urobiome alterations are present during acute rejection in renal transplant recipients.
View Article and Find Full Text PDFDiagnostic performance of dual-energy computed tomography (DECT) quantitative parameters for detecting metastatic cervical lymph nodes in patients with papillary thyroid cancer: A systematic review and meta-analysis.
Eur J Radiol
January 2025
Department of Radiology, Hebei General Hospital, 348 Heping West Road, Shijiazhuang 050051, Hebei, China. Electronic address:
Purpose: This study systematically evaluated the diagnostic performance of dual-energy computed tomography (DECT) quantitative parameters in detecting cervical lymph node metastasis in patients with papillary thyroid cancer (PTC).
Method: We searched PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, and Wanfang Data databases for relevant original studies from database inception to March 2024. The quality of the included studies was evaluated using the QUADAS-2 tool.
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