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Severe Varicella-Zoster Virus Pneumonia in an Unvaccinated Patient With Rheumatoid Arthritis: A Case Report and Literature Review.
Cureus
November 2024
Respiratory Medicine, Handa City Hospital, Handa, JPN.
The global prevalence of rheumatoid arthritis (RA) is increasing, resulting in an increased use of Janus kinase (JAK) inhibitors. Several cases of varicella-zoster virus (VZV) pneumonia in patients with RA have been reported. However, to our knowledge, no reports have demonstrated conclusive evidence of VZV reinfection in this patient population.
View Article and Find Full Text PDF[Herpes zoster : vaccination and management of satellite lesions in immunocompromised patients].
Rev Med Liege
December 2024
Service de Dermatologie et Vénéréologie, CHU Liège, Belgique.
Shingles, also termed herpes zoster (HZ), is due to the reactivation of the varicella zoster virus (VZV) in a dorsal root nerve ganglion with an intra-axonal passage of the virus to a predetermined dermatome. The risk of HZ increases with age, as well as the morbidity risks. The most feared complication is post-herpetic neuralgia, defined as persisting pain sensations three months after the resolution of the skin lesions.
View Article and Find Full Text PDFA prospective, multi-center post-marketing surveillance cohort study to monitor the safety of the recombinant zoster vaccine in Chinese adults ≥50 years of age.
Hum Vaccin Immunother
December 2024
GSK, Rockville, USA.
This post-marketing surveillance study evaluated the safety of the adjuvanted recombinant zoster vaccine (RZV) in Chinese adults, given the limited country-specific safety data accumulated since the 2019 licensure of RZV in China for adults ≥ 50 years of age (YOA). This descriptive, prospective cohort study enrolled adults ≥ 50 YOA who voluntarily received RZV per routine clinical practice in six centers in China. The primary outcomes were occurrence, intensity, and causal relationship to vaccination of medically attended adverse events (MAEs) within 30 days post-any dose.
View Article and Find Full Text PDFChickenpox in Poland in 2022.
Przegl Epidemiol
December 2024
Zakład Epidemiologii Chorób Zakaźnych i Nadzoru, NIZP PZH - PIB.
Introduction: Chickenpox is an infectious disease caused by the Varicella-zoster virus, usually affecting children. It is characterized by a rash with rapid seeding of small red papules. The course of the disease is mild, but in people with weakened immunity it may be severe.
View Article and Find Full Text PDFAnalysis of sero-epidemiological characteristics of varicella in healthy children in Wuxi, China.
Hum Vaccin Immunother
December 2024
Wuxi Center for Disease Control and Prevention, The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi, China.
Article Synopsis
- * Out of 697 serum samples tested, 67.84% showed antibody positivity with a geometric mean concentration (GMC) of 190.97 mIU/mL, indicating strong immune response in vaccinated children.
- * The findings suggest that two doses of VarV significantly improve immunity against varicella compared to those unvaccinated, but anti-body levels decreased four years post-vaccination, highlighting the need for VarV in national immunization strategies.
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