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A new triterpenoid saponin from predicted by NMR-based mosaic method. | LitMetric

A new triterpenoid saponin from predicted by NMR-based mosaic method.

Nat Prod Res

Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.

Published: April 2020

A saponin () with gypsogenin as aglycone was isolated from the roots of . The aglycone of compound was considered as gypsogenin which was rarely found in this genus. Its structure was predicted by NMR-based "mosaic" method rapidly, and further confirmed on the basis of spectroscopic data, including 2D NMR spectra and chemical evidence. This work suggested that NMR-based mosaic method is suitable for most of saponins from common species of genus .

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Source
http://dx.doi.org/10.1080/14786419.2018.1538995DOI Listing

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