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Contribution of rare mutational outcomes to broadly neutralizing antibodies.
Acta Biochim Biophys Sin (Shanghai)
May 2022
Antibodies are important immune molecules that are elicited by B cells to protect our bodies during viral infections or vaccinations. In humans, the antibody repertoire is diversified by programmed DNA lesion processes to ensure specific and high affinity binding to various antigens. Broadly neutralizing antibodies (bnAbs) are antibodies that have strong neutralizing activities against different variants of a virus.
View Article and Find Full Text PDFA Radiomics Approach to Predict the Emergence of New Hepatocellular Carcinoma in Computed Tomography for High-Risk Patients with Liver Cirrhosis.
Diagnostics (Basel)
September 2021
Department of Diagnostic and Interventional Radiology, University Hospital, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.
Liver cirrhosis poses a major risk for the development of hepatocellular carcinoma (HCC). This retrospective study investigated to what extent radiomic features allow the prediction of emerging HCC in patients with cirrhosis in contrast-enhanced computed tomography (CECT). A total of 51 patients with liver cirrhosis and newly detected HCC lesions ( = 82) during follow-up (FU-CT) after local tumor therapy were included.
View Article and Find Full Text PDF[Tinea corporis within recent tattoos].
Ann Dermatol Venereol
October 2020
Consultation « tatouages », service de dermatologie, hôpital Bichat, Assistance publique-Hôpitaux de Paris, 46, rue Henri-Huchard, 75877 Paris cedex 18, France; Department of dermatology, allergology and venereology, Helsinki university hospital, Meilahdentie 2, PO Box 160, 00029 Helsinki, Finlande. Electronic address:
Introduction: Tattoos are occasionally associated with cutaneous infections. Diagnosis can be challenging as the clinical presentation of such infections may differ from those on plain skin. Herein we report an atypical form of tinea corporis restricted to two recent tattoos during healing, caused by environmental contamination.
View Article and Find Full Text PDFImplementation of the Dutch expertise centre for child abuse: descriptive data from the first 4 years.
BMJ Open
August 2019
General Paediatrics, University Medical Center Utrecht, Utrecht, The Netherlands.
Objective: Combined paediatric and forensic medical expertise to interpret physical findings is not available in Dutch healthcare facilities. The Dutch Expertise Centre for Child Abuse (DECCA) was founded in the conviction that this combination is essential in assessing potential physical child abuse. DECCA is a collaboration between the three paediatric hospitals and the Netherlands Forensic Institute.
View Article and Find Full Text PDFImprobable lesion in a child.
J Paediatr Child Health
December 2018
Department of Dermatovenereology, Hospital de Braga, Braga, Portugal.
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