Isolated cleft palate without cleft lip is a rare deformity. Cleft lip and cleft palate can sometimes develop in combination with a syndrome due to genetic causes. Affected patients have morbidity through life from birth and experience comprehensive treatment for such clefts including surgery. It is extremely rare that the untreated clefts are found during routine cadaveric dissection, since many patients have treatment for clefts in developed countries. Herein, we present a case of an untreated incomplete isolated cleft palate on the right side of the maxilla. An oronasal fistula was found in the same location as the missing right maxillary lateral incisor, and the soft palate was considerably intruding into the hard palate but without penetration into the nasal cavity. The right incisivus labii superioris muscle forming the oral vestibule was incompletely torn with two fistulae. An incomplete bony defect was found on the right maxilla without oronasal or oroantral fistula. This paper may contribute to evaluating the disturbed site of the incomplete isolated cleft palate with no treatment.
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http://dx.doi.org/10.1007/s12565-018-00471-1 | DOI Listing |
Logoped Phoniatr Vocol
January 2025
Department of Rehabilitation Sciences, Centre of Speech and Language Sciences Ghent University, Gent, Belgium.
Introduction: This descriptive study investigated the immediate individual effects of intensive group speech intervention on speech, health-related quality of life, and satisfaction in adolescents born with a cleft (lip and) palate (CP ± L) in the Philippines.
Methods: Four Filipino adolescents with a repaired CP ± L (age range = 17 to 23 years) were included. They presented with at least one cleft-related speech sound error.
Cleft Palate Craniofac J
January 2025
Department of Plastic, Reconstructive and Hand Surgery, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands.
CAAs are congenital malformations of the auricle ranging from ear underdevelopment to anotia, lacks standardized classification, impacting our outcome of different reconstruction approaches. This scoping review aimed to explore which CAA classifications are most used in current ear reconstruction practices. We conducted a scoping review following the PRISMA guidelines, searching MEDLINE and Embase databases on November 1st, 2023.
View Article and Find Full Text PDFCleft Palate Craniofac J
January 2025
Department of Orofacial Sciences and Orthodontics, Division of Craniofacial Anomalies, School of Dentistry, University of California, San Francisco, CA, USA.
The purpose of this study was to quantitatively assess the alveolar bone support of teeth adjacent to the cleft site in individuals with nonsyndromic cleft lip and palate (CLP) who have undergone either orthodontic space closure or space opening for missing lateral incisors. A cross-sectional retrospective study. University orthodontic clinic serving individuals with CLP.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Laboratory for Oral Molecular Biology, Department of Orthodontics and Dentofacial Orthopedics, University of Bern, Freiburgstrasse 3, Bern, 3010, Switzerland.
Background: Epidemiologic data on the number of cleft lip and/or palate (orofacial cleft (OFC)) births in Switzerland are currently sparse. However, this knowledge is essential for better understanding the etiologies underlying the various cleft phenotypes and providing expectant parents with the best possible healthcare planning and counseling.
Methods: This is the first descriptive study to report data on the prevalence of the various cleft types, their sex, and regional distributions in Switzerland.
Nat Commun
January 2025
State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.
Little is known about the regulation and function of phase separation in craniofacial developmental disorders. MSX1 mutations are associated with human cleft palate, the most common craniofacial birth defect. Here, we show that MSX1 phase separation is a vertebrate-conserved mechanism underlying embryonic palatal fusion.
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