AI Article Synopsis
- A model is being developed to evaluate how effective various anti-bacterial coatings are on complex metal implants within a bone environment.
- The study focuses on designing porous titanium implants specifically for implantation in the proximal tibia of rats, with adjustments made to implant length, diameter, and porosity based on tests with cadaver specimens.
- The research identifies key parameters necessary for inducing chronic implant infections in Sprague Dawley rats, examining different bacterial strains and inoculation doses.
Article Abstract
A model is needed to study the effectiveness of different anti-bacterial coatings on complex metal implants in a bone environment. This article shares data on the design of porous titanium implants for intramedullary implantation in the proximal rat tibia. The implant length, diameter and porosity were optimized after testing on cadaveric specimens. This article shares data on which parameters are critical to establish a chronic implant infection in Sprague Dawley rats when using the new implant design. To this end, different strains of and inoculation doses were investigated.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247446 | PMC |
| http://dx.doi.org/10.1016/j.dib.2018.10.157 | DOI Listing |
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