AI Article Synopsis

  • Imaging is crucial in prostate cancer for assessing the disease's local spread, lymph node involvement, and metastases.
  • Bone scans are widely used for detecting bone metastases but are less sensitive and specific compared to MRI, which is considered the best option.
  • In a case study, a patient showed signs of skeletal metastases on MRI, but both the bone scan and Ga PSMA PET-CT tests were negative, and histology confirmed there were no metastases.

Article Abstract

Imaging in prostate cancer is important in defining the local extent of disease, nodal involvement, and identifying metastases. Bone scan is the most commonly used modality for identification of bone metastasis in prostate cancer despite its reported low sensitivity and specificity compared to magnetic resonance imaging (MRI) which is the imaging gold standard for bone metastasis. Gallium-68 prostate-specific membrane antigen positron emission tomography-computed tomography (Ga PSMA PET-CT) imaging is a relatively new addition to the imaging modalities in prostate cancer. This is a report of a patient with high-risk prostate cancer with features consistent with skeletal metastases on MRI but negative for skeletal metastases on bone scan and Ga PSMA PET CT. Histology confirmed the absence of skeletal metastases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216739PMC
http://dx.doi.org/10.4103/wjnm.WJNM_89_17DOI Listing

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