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[Cutaneous ulcer as the initial manifestation of rheumatoid arthritis. Case report].
Rev Med Inst Mex Seguro Soc
May 2024
Instituto Mexicano del Seguro Social, Hospital de Traumatología y Ortopedia de Puebla, Servicio de Medicina Interna. Puebla, Puebla, México.
Background: 20-40% of patients with rheumatoid arthritis (RA) present an extra-articular manifestation (EAM) and 1-20% a severe EAM, with an increased risk of death (> 2 times). The associated lesions are: 27.5% rheumatoid nodules, and 0.
View Article and Find Full Text PDFStratified Mucin-producing Lesions of the Anus: Insights into an Emerging Histologic Type of HPV-driven Anal Neoplasia.
Am J Surg Pathol
September 2024
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
Primary anal cancers are rare and typically driven by high-risk human papillomavirus (HPV) infection. Though squamous cell carcinoma is most common, a spectrum of HPV-related nonsquamous anogenital neoplasms with similarities to cervical stratified mucin-producing carcinoma has been reported. In this study, we mined our institutional archives to characterize the clinicopathologic features of this emerging entity.
View Article and Find Full Text PDFBeyond rheumatoid nodules in rheumatoid arthritis.
ARP Rheumatol
October 2024
Unidade Local de Saúde de Coimbra.
Article Synopsis
- - Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects joints but can also lead to skin issues, with rheumatoid nodules being the most common skin manifestation in 20-30% of affected individuals.
- - Palisaded neutrophilic granulomatous dermatitis (PNGD) is a less common skin condition that can occur in RA patients, characterized by red, itchy bumps on the skin that are difficult to distinguish from rheumatoid nodules without a biopsy.
- - A 71-year-old woman with RA developed PNGD, emphasizing the need for collaboration between rheumatology and dermatology for proper diagnosis and effective treatment, which may include corticosteroids and managing the underlying RA.
Surgical Excision of Palisaded Neutrophilic and Granulomatous Dermatitis of the Vulva: A Case Report.
Cureus
July 2024
Pathology, King Abdulaziz University Faculty of Medicine, Rabigh Branch, Jeddah, SAU.
Palisaded neutrophilic and granulomatous dermatitis (PNGD) is an inflammatory cutaneous disorder of unknown etiology that typically occurs in association with systemic disease. Rheumatoid arthritis and systemic lupus erythematosus are the most common associated diseases. PNGD manifests as skin-colored to erythematous papules and plaques, mainly on the extremities.
View Article and Find Full Text PDFPyoderma Gangrenosum: A Presenting Feature of Rheumatoid Arthritis.
Cureus
July 2024
Dermatology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune (Deemed to Be University), Pune, IND.
Article Synopsis
- Pyoderma gangrenosum (PG) is a rare inflammatory disorder with diverse symptoms and is often linked to conditions like inflammatory bowel disease.
- A case study of a 65-year-old woman revealed PG manifested as multiple ulcers on her body, leading to further examination for underlying causes.
- The diagnosis of rheumatoid arthritis (RA) was established through testing, highlighting that many patients with PG may have undiagnosed RA, especially when they seek help for ulcers on their lower limbs.
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