AI Article Synopsis
- * This approach enhances sensitivity and spectral resolution while allowing for real-time measurement of coupling constants (J) using a homodecoupled method.
- * Additionally, a novel J-resolved HSQC experiment is introduced for easy and automated determination of these coupling constants from a 2D spectrum.
Article Abstract
The concepts of pure-shift NMR and time-shared NMR are merged in a single experiment. A C/N time-shared version of the real-time BIRD-based broadband homodecoupled HSQC experiment is described. This time-efficient approach affords simultaneously H-C and H-N pure-shift HSQC spectra in a single acquisition, while achieving substantial gains in both sensitivity and spectral resolution. We also present a related C/N-F2-coupled homodecoupled version of the CLIP-HSQC experiment for the simultaneous measurement of J and J from the simplified doublets observed along the direct dimension. Finally, a novel J-resolved HSQC experiment has been designed for the simple and automated determination of both J/J from a 2D J-resolved spectrum.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jmr.2018.11.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!