Objective: To determine the changes in the retinal nerve fiber layer as measured on optical coherence tomography (OCT) after phacoemulsification with intraocular lens implantation.
Study Design: Quasi-experimental study.
Place And Duration Of Study: Department of Ophthalmology, Lahore General Hospital, Lahore, from March 2017 to April 2018.
Methodology: All patients (n=64) diagnosed with cataract and requiring surgery were included in study. Patients having any coexisting ocular pathology hindering the OCT measurement, i.e. corneal opacity, vitreous hemorrhage, retinal detachment etc. were excluded from study. Retinal nerve fiber layer thickness was measured in four quadrants. Signal strength on OCT was also documented. Preoperatively, visual acuity was measured, OCT performed, and the findings were recorded on a designed proforma. Postoperatively, the patients followed up after one month for visual acuity and OCT measurement.
Results: Retinal nerve fiber layer thickness was increased postoperatively as measured on OCT as did the signal strength. The increase was statistically significant (p <0.001).
Conclusion: Removal of cataract by surgery enhances the OCT measurement of retinal nerve fiber layer, resulting in increased thickness.
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http://dx.doi.org/10.29271/jcpsp.2018.12.919 | DOI Listing |
Heliyon
July 2024
D-Eye Srl, Padova, 35131, Italy.
Widespread screening is crucial for the early diagnosis and treatment of glaucoma, the leading cause of visual impairment and blindness. The development of portable technologies, such as smartphone-based ophthalmoscopes, able to image the optical nerve head, represents a resource for large-scale glaucoma screening. Indeed, they consist of an optical device attached to a common smartphone, making the overall device cheap and easy to use.
View Article and Find Full Text PDFNarra J
December 2024
Department of Clinical Pathology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Obesity and retinal microvasculature dysfunction are linked and impact visual acuity. The aim of this study was to determine the relationship between the HOMA-IR score and the presence of vascular dysfunction (capillary perfusion and flux index) of the optic nerve head (ONH) of the retina in obese patients and to determine its diagnostic performance to predict vascular dysfunction. A case-control study was conducted in 2022 involving individuals from obese and non-obese groups.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
January 2025
Department of Ophthalmology, Fuyang Hospital Affiliated to Bengbu Medical University(Fuyang People's Hospital), Fuyang, 236400, Anhui Province, China. Electronic address:
Purpose: To evaluate optic disc and macular microvasculature changes in children with anisometropic amblyopia before and after treatment.
Methods: In all, 60 children with unilateral anisometropic amblyopia between the ages of 6 and 12 were randomly selected from the ophthalmology clinic of Fuyang People's Hospital, while 60 children with non-amblyopia in the same age range were randomly selected as a normal control group. The right eye was uniformly taken in the control group with at least 6 months of follow-up.
J Infect Dis
January 2025
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.
Cryptococcus gattii is a saprophytic basidiomycete that grows in the environment and can cause systemic cryptococcosis. Ocular cryptococcosis causes blindness and is commonly associated with central nervous system (CNS) infection. Toll-like receptor 9 (TLR9) can control cryptococcosis and another mycosis.
View Article and Find Full Text PDFJ Neurol
January 2025
Jacobs Comprehensive MS Treatment and Research Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Background: Previous investigations on optical coherence tomography (OCT) in multiple sclerosis (MS) focused on generalizable macular and peri-papillary regions without considering the anatomic variations of the retinal layer thickness.
Objective: This study aimed to assess the utility of parafoveal retinal layer thickness measured by OCT, underscoring its relationships with clinical outcomes in MS.
Methods: In this cross-sectional study, 214 people with MS (pwMS) and 57 age- and sex-matched healthy controls (HCs) were enrolled.
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