To investigate the resilience of caregivers of people with mild and moderate Alzheimer's disease (PwAD) and the related sociodemographic and clinical characteristics. Cross-sectional assessment of dyads of PwAD and family caregivers ( = 106). Caregivers were assessed for resilience, depression, anxiety, hopelessness, quality of life, burden and cognition. PwAD were assessed for severity of dementia, cognition, neuropsychiatric symptoms, functionality, quality of life and awareness of disease. Most of the caregivers (51.1%) reported emotional problems (symptoms of anxiety, stress and depression). In both mild ( < 0.05) and moderate ( < 0.05) PwAD groups, resilience was inversely related to self-reported emotional problems. There was not a significant difference between caregivers of mild and moderate PwAD resilience ( < 0.05). Upon analyzing the factors related to resilience, we found some differences between the groups of caregivers of mild and moderate PwAD. Neuropsychiatric symptoms of PwAD ( < 0.05) and caregiver's depressive symptoms ( < 0.05) were related to resilience of caregivers of mild PwAD. In the moderate group, caregivers' higher levels of quality of life ( < 0.05) and co-residing with PwAD ( < 0.05) were related to resilience. Caregivers' resilience is driven by different factors according to disease severity. The findings suggest that resilience allows caregivers to manage and respond positively to stressful demands of care.
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http://dx.doi.org/10.1080/13607863.2018.1533520 | DOI Listing |
Severe aortic valve stenosis poses a significant risk for the aging population, often escalating from mild symptoms to life-threatening heart failure and sudden death. Without timely intervention, this condition can lead to disastrous outcomes. The advent of transcatheter aortic valve implantation (TAVI) has gained popularity, emerging as an effective alternative for managing severe aortic stenosis (AS) in high-risk patients experiencing deterioration of previously implanted bioprosthetic surgical aortic valves (SAV), which introduces complex challenges such as device compatibility and anatomical considerations.
View Article and Find Full Text PDFJuntendo Iji Zasshi
December 2024
Objectives: This study focuses on mild-to-moderate severity cases to examine the triggers initiating kidney injury.
Materials: Patients aged ≥18 years with suspected heat-related illnesses at the Juntendo University Hospital Emergency and Primary Care Center between July and September 2020 and June and August 2022 were included.
Methods: Blood samples were obtained during their visit, and the patients were categorized into two groups based on their cystatin-based estimated GFR (eGFRcys) values: a kidney injury group (eGFRcys < 60 mL/min/1.
Front Oncol
January 2025
Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Tumor Treating Fields (TTFields) has emerged as a significant adjunctive component in the treatment of high-grade gliomas following the EF-14 trial in 2017. The incorporation of TTFields, alongside cyclic temozolomide therapy, has demonstrated improved patient outcomes when the usage exceeds 18 h per day (75% usage). analysis of the EF-14 trial has demonstrated that therapy usage exceeding 90% is associated with an additional benefit, while rates above 50% have also proven effective in literature.
View Article and Find Full Text PDFJ Ophthalmol
January 2025
Pediatric Ophthalmology, Shanxi Aier Eye Hospital, Aier Eye Hospital Group, Changsha, China.
To investigate the correlation between corneal biomechanical characteristics and refractive status in adolescents aged 5-13 years. A cross-sectional study involved 339 children aged 5-13 with a spherical equivalent (SE) range from -6.00 to +2.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Shenzhen Eye Institute, Shenzhen Eye Hospital, Jinan University, Shenzhen, Guangdong, China.
Objective: This study aims to explore the differences in ocular parameters among adult myopic patients with different degrees of myopia and axial lengths, and to investigate the correlations between these ocular parameters.
Methods: This single-center observational study collected clinical data from myopic patients aged 18-45 years who visited the Eye Hospital of Nanjing Medical University between January and June 2023. The data included laterality, diopter of spherical power (DS), diopter of cylindrical power (DC), spherical equivalent (SE), axial length (AL), central corneal thickness (CCT), flat meridian keratometry (K1), steep meridian keratometry (K2), mean keratometry (Km), anterior chamber depth (ACD), corneal radius of curvature (CRC), and axial length/corneal radius of curvature ratio (AL/CRC).
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