Standard Approach to Gastrointestinal Stromal Tumors - Differences between China and Europe.

Visc Med

Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Published: October 2018

AI Article Synopsis

  • Gastrointestinal stromal tumors (GISTs) are the most common type of mesenchymal tumors found in the gastrointestinal tract, and advancements in molecular-targeted therapies have made them a key focus in cancer treatment.
  • There are established clinical guidelines for GISTs in Europe, particularly from the European Society of Medical Oncology (ESMO), but these guidelines may not fit the unique clinical context and practices in China.
  • This review highlights the differences between Chinese GIST consensus guidelines and European guidelines, aiming to improve diagnosis and management strategies for GIST patients in China.

Article Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. With the considerable research and application of molecular-targeted therapy for GISTs in the last two decades, GISTs have become a model of multidisciplinary oncological treatment. Although Western clinical guidelines are available for GISTs, such as those by the European Society of Medical Oncology (ESMO), the clinical situations in China are different from those in European countries. There are distinct differences between the clinical practice, diagnostic methods, surgical approach, and availability of new targeted agents in China and those in Europe. This review summarizes the Chinese GIST consensus guidelines compared to the European ones, which may provide an optimal approach to the diagnosis and management of GIST patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257205PMC
http://dx.doi.org/10.1159/000494347DOI Listing

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