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Efficacy and safety of first- and second-line antibiotics for cellulitis and erysipelas: a network meta-analysis of randomized controlled trials.
Arch Dermatol Res
September 2024
Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, Hubei, 430022, P.R. China.
Article Synopsis
- - The study conducted a network meta-analysis to assess and rank the effectiveness of various first- and second-line antibiotics for treating cellulitis and erysipelas, analyzing data from 10 randomized clinical trials involving 1,936 patients up to July 2024.
- - For cellulitis, cefaclor had the best curative outcomes, while ceftriaxone was noted for having the fewest gastrointestinal side effects like diarrhea or vomiting.
- - In treating erysipelas, pristinamycin exhibited the highest cure rates but also carried a greater risk of causing rash, highlighting the need for further research on optimizing antibiotic choices for these skin infections.
The Use of Shells of Marine Molluscs in Spanish Ethnomedicine: A Historical Approach and Present and Future Perspectives.
Pharmaceuticals (Basel)
October 2023
Departamento de Anatomía Patológica, Biología Celular, Histología, Historia de la Ciencia, Medicina Legal y Forense y Toxicología, Área de Historia de la Ciencia, Facultad de Medicina, Universidad de Cádiz, E-11003 Cádiz, Spain.
Since ancient times, the shells of marine molluscs have been used as a therapeutic and/or prophylactic resource. In Spain, they were part of practical guides for doctors or pharmacists until the 19th century. In general, seashells were prepared by dissolving in vinegar and were part of plasters or powders used as toothpaste, or to treat dyspepsia, heartburn and leprosy.
View Article and Find Full Text PDFTraditional uses, bioactive composition, pharmacology, and toxicology of Phyllanthus emblica fruits: A comprehensive review.
J Ethnopharmacol
January 2022
Faculty of Applied Sciences and Biotechnology, Shoolini University, Post Box No. 9, Head Post Office, Solan, H.P., India. Electronic address:
Ethnopharmacological Relevance: The fruits of Phyllanthus emblica Linn or Emblica officinalis Gaertn (Phyllanthaceae), (FPE) commonly known as Indian gooseberry or Amla, gained immense importance in indigenous traditional medicinal systems, including Ayurveda, for its medicinal and nutritional benefits. It is used to cure several diseases such as common cold, fever, cough, asthma, bronchitis, diabetes, cephalalgia, ophthalmopathy, dyspepsia, colic, flatulence, hyperacidity, peptic ulcer, erysipelas, skin diseases, leprosy, hematogenesis, inflammation, anemia, emaciation, hepatopathy, jaundice, diarrhea, dysentery, hemorrhages, leucorrhea, menorrhagia, cardiac disorders, and premature greying of hair.
Aim Of The Study: In the present review, we presented a comprehensive analysis of the ethnopharmacology, bioactive composition, and toxicity of P.
The Intriguing History of Cancer Immunotherapy.
Front Immunol
November 2020
Chair and Department of Medical Microbiology, Medical University of Warsaw, Warsaw, Poland.
Immunotherapy is often perceived as a relatively recent advance. In reality, however, one should be looking for the beginnings of cancer immunotherapy under different names as far as in the Antiquity. The first scientific attempts to modulate patients' immune systems to cure cancer can be attributed to two German physicians, Fehleisen and Busch, who independently noticed significant tumor regression after erysipelas infection.
View Article and Find Full Text PDFIs coverage of S. aureus necessary in cellulitis/erysipelas? A literature review.
Infection
April 2020
Infectious Diseases Unit, School of Medicine, University of Crete, Voutes, Heraklion, Postal code 71110, Greece.
Background: Empirical treatment of patients with cellulitis/erysipelas usually targets both streptococci and methicillin-sensitive S. aureus (MSSA). However, the recommendation to empirically cover MSSA is weak and based on low-quality evidence.
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