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An experimental and computational approach to evaluate the antidiabetic activity of Commiphora wightii gum extract.
J Ayurveda Integr Med
December 2024
Department of Microbiology & Biotechnology, IIS (deemed to be University), Jaipur, 302020, India. Electronic address:
Background: Plant formulations with antidiabetic and antioxidant properties have recently gained popularity due to their lower cost and lesser side effects. Guggul gum is one such formulation that is extensively being used to cure various ailments.
Objective: The present study was designed to explore the antioxidant and antidiabetic properties of the aqua-ethanolic Guggul gum extract (GE) from Commiphora wightii using in silico studies and in vitro assays.
A Standardized Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study.
J Am Nutr Assoc
December 2024
Department of Orthopedics, Meher Hospital, Gandhinagar, Vijayawada, India.
Background And Objective: Roxb. ex Colebr. (Family: Burseraceae; Genus: Boswellia) gum resin (Salai guggul) has profound therapeutic value in Ayurvedic and Unani medicines in alleviating several chronic inflammatory illnesses, including arthritis, asthma, skin and blood diseases, fever, etc.
View Article and Find Full Text PDFSynthesis of bimetallic oxides (SrO-CoO) nanoparticles decorated polyacrylamide hydrogels for controlled drug release and wound healing applications.
Int J Biol Macromol
August 2024
Department of Physics, College of Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia. Electronic address:
Hydrogels are polymeric structures characterized by their three-dimensional nature, insolubility in aqueous media, and remarkable ability to absorb significant amounts of water. Owing to their exceptional biocompatibility with living tissues, hydrogels find extensive use in various biomedical applications. Guggul gum grafted polyacrylamide hydrogels (SG) were prepared and green synthesized SrO, CoO and SrO-CoO nanoparticles (NPs) were incorporated with hydrogels (SrG, CoG, Sr-CoG) respectively.
View Article and Find Full Text PDFOptimization of antimicrobial nanocomposite films based on carboxymethyl cellulose incorporating chitosan nanofibers and Guggul gum polysaccharide.
Sci Rep
June 2024
Department of Food Hygiene and Aquaculture, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
The present study utilized response surface methodology (RSM) to investigate the impact of varying concentrations of carboxymethyl cellulose (CMC: 0.75-1.75 wt%), Commiphora mukul polysaccharide (CMP: 0-1 wt%), and Chitosan Nanofiber (CHNF: 0-1 wt%) on the physical and antimicrobial characteristics of nanocomposite films based on CMC.
View Article and Find Full Text PDFExploring the Promising Role of Guggulipid in Rheumatoid Arthritis Management: An In-depth Analysis.
Curr Rheumatol Rev
July 2024
Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, Madhya Pradesh, 470003, India.
Background: Guggulipid, an oleo-gum resin extracted from the bark of of the Burseraceae family, holds a significant place in Ayurvedic medicine due to its historical use in treating various disorders, including inflammation, gout, rheumatism, obesity, and lipid metabolism imbalances.
Objective: This comprehensive review aims to elucidate the molecular targets of guggulipids and explore their cellular responses. Furthermore, it summarizes the findings from , and clinical investigations related to arthritis and various inflammatory conditions.
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