: Significant medical benefits could be derived from universal AMH screening for women in their mid to late twenties. We aimed to investigate the psychological and emotional responses of women to being informed of their anti-Mullerian hormone (AMH) result with a view to informing the possible introduction of universal AMH screening.: This was a prospective qualitative study using semi-structured in-depth interviews of women attending a reproductive medicine clinic who had ovarian reserve testing performed via measurement of serum AMH levels, as part of their gynecological investigations. A semistructured interview schedule was developed after a review of the literature. A purposive sample of women was recruited, and data collection continued until thematic saturation was reached ( = 10). The number of women interviewed is low as this was a pilot qualitative study of a two-part study. The next part of the study involves the development of a quantitative questionnaire related to the key themes identified in this study to be based on a much larger group of women. Interviews were audiotaped, transcribed verbatim and imported into QSR NVivo pro 11 for analysis. Three key themes emerged from the data: the experience of AMH testing, the response to the AMH result, and suggested lessons for medical professionals. The theme of the experience of AMH testing describes and reflects two sub-themes: the reasons for ovarian reserve testing and the potential barriers that may prevent women from accessing testing. A further key focus of this study was the emotional and psychological responses to receiving an AMH result and this emerged as a major theme in the interviews. Women described the significant impact that their individual result had on a number of lifestyle and behavioral factors and how it impacted on their gender identity. Lessons for medical professionals including the appreciation of the patient's awareness of the test and how the test result was relayed to the patient were important factors in how they dealt with the result. There were mixed reactions and opinions from the group in relation to the introduction of AMH testing as a screening tool for all young women. Knowledge and communication of a low AMH result has a negative psychological impact. The findings from this study support the move to further explore the psychological and emotional impact of the test with the development of a quantitative questionnaire.
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http://dx.doi.org/10.1080/0167482X.2018.1541980 | DOI Listing |
Background: Differential diagnosis of hypogonadotropic hypogonadism (HH) and constitutional delay of puberty (CDP) is extremely important since with the latter puberty begins and completes without any medical intervention and in the case of HH puberty does not occur or is incomplete. Failure to start treatment on time leads to medical and psychosocial maladjustment of the patient.
Aim: Development of a method for differential diagnosis of hypogonadotropic hypogonadism and constitutional delay of puberty in boys 13.
Int J Womens Health
January 2025
Women 's Health Department, Xicheng District Maternal and Child Health Care Hospital, Beijing, 100054, People's Republic of China.
Purpose: This study aimed to analyze the distribution and factors influencing anti-Müllerian hormone (AMH) levels among family-planning women of childbearing age in Beijing, China.
Patients And Methods: We collected the data of 3,236 family-planning women of childbearing age who underwent pre-pregnancy examinations at Xicheng District Maternal and Child Health Hospital in Beijing between October 2021 and July 2024. Collected data included age, education level, ethnicity, height, weight, and systolic and diastolic blood pressure.
Int J Gynaecol Obstet
January 2025
Center for Reproductive Medicine, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Objective: Polycystic ovary syndrome (PCOS) is a diverse condition with an unknown cause. The precise mechanism underlying ovulatory abnormalities in PCOS remains unclear. It is widely believed that malfunction of granulosa cells is the primary factor contributing to aberrant follicular formation in PCOS.
View Article and Find Full Text PDFReprod Biol Endocrinol
January 2025
Reproductive Medicine Center, Zhuhai Maternal and Child Health Care Hospital, 543 Ningxi Road, Zhuhai, 519000, China.
Purpose: Prior sperm DNA fragmentation index (DFI) thresholds for diagnosing male infertility and predicting assisted reproduction technology (ART) outcomes fluctuated between 15 and 30%, with no agreed standard. This study aimed to evaluate the impact of the sperm DFI on early embryonic development during ART treatments and establish appropriate DFI cut-off values.
Methods: Retrospectively analyzed 913 couple's ART cycles from 2021 to 2022, encompassing 1,476 IVF and 295 ICSI cycles, following strict criteria.
Nucl Med Biol
January 2025
Central Research Laboratory, Hamamatsu Photonics K.K., Hamana, Hamamatsu, Shizuoka 434-8601, Japan.
Background: The ovary is an important female organ not only for pregnancy but also for the regulation of life activities via hormone release. Ovarian function is measured by blood hormone levels, but the hormone level reflects only the ovarian reserve and no other essential ovarian functions, such as nurturing and expelling follicles. Ovarian fibrosis is related to essential ovarian function; however, the existing methods for evaluating fibrosis are invasive.
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