In this study, we investigated the effect of sintering temperature (1300, 1350, or 1400 °C) and holding time (1 or 2 h) on the mechanical properties of a cobalt-chromium (Co-Cr) alloy (Soft Metal) produced by milling/post-sintering, using a tensile test ( = 6). Prior to the test, the different nanostructures arising from the sintering conditions were also analyzed. The phase ratio of (face-centered cubic) phase to (hexagonal close-packed) phase increased mainly with increasing temperature. The formation of CrC carbide was greatest in the 1350 °C groups when compared to the other temperature groups. The 1400 °C groups had a substantially greater grain size than the 1300 °C and 1350 °C groups, together with a significant number of annealing twins inside the matrix phases. Overall, the 1350 °C groups showed the most superior properties. The 1400 °C groups showed a mean 0.2% yield strength under 500 MPa. The holding times did not significantly affect the mechanical properties ( > 0.05).
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http://dx.doi.org/10.1166/jnn.2019.15984 | DOI Listing |
Acta Pharmacol Sin
January 2025
National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangdong Province Engineering Laboratory for Druggability and New Drug Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
Sorting nexins (SNXs) as the key regulators of sorting cargo proteins are involved in diverse diseases. SNXs can form the specific reverse vesicle transport complex (SNXs-retromer) with vacuolar protein sortings (VPSs) to sort and modulate recovery and degradation of cargo proteins. Our previous study has shown that SNX3-retromer promotes both STAT3 activation and nuclear translocation in cardiomyocytes, suggesting that SNX3 might be a critical regulator in the heart.
View Article and Find Full Text PDFJ Bone Miner Res
January 2025
Departments of Medicine and Radiology, University of Manitoba, Winnipeg, Canada.
Vertebral fracture assessment (VFA) images from bone density machines enable the automated machine learning assessment of abdominal aortic calcification (ML-AAC), a marker of cardiovascular disease (CVD) risk. The objective of this study was to describe the risk of a major adverse cardiovascular event (MACE, from linked health records) in patients attending routine bone mineral density (BMD) testing and meeting specific criteria based on age, BMD, height loss, or glucocorticoid use have a VFA in the Manitoba Bone Mineral Density Registry. The cohort included 10 250 individuals (mean 75.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Horticultural Sciences, Faculty of Agriculture, Urmia University, Urmia, Iran.
In this study, screening of the collected 70 Salvia nemorosa L. populations from 54 habitats from West Azerbaijan province, Iran was evaluated by analyzing the content of phytochemical compounds, antioxidant activity, and UHPLC-HRMS profiling in different populations. The aerial parts of the plants were analyzed based on total phenolic (TPC) and flavonoid (TFC), total tannin (TTC), ascorbic acid (AAC), chlorophylls (Cla, and Clb), total carotenoid (TCC), β-carotene, antioxidant activity (by DPPH and FRAP assays), and 40 polyphenolic compounds by UHPLC-HRMS (phenolic acids, flavonoids and fatty acyl glicosides).
View Article and Find Full Text PDFBMC Genomics
December 2024
School of Life Sciences, Hebei University, Baoding, Hebei, 071000, China.
Background: Myogenic factor 6 (Myf6) plays an important role in muscle growth and differentiation. In aquatic animals and livestock, Myf6 contributes to improving meat quality and strengthening the accumulation of muscle flavor substances. However, studies on Myf6 gene polymorphisms in crustaceans have not been reported.
View Article and Find Full Text PDFPol J Vet Sci
June 2024
Department of Surgery, Faculty of Veterinary Medicine, University of Siirt, Kezer Campus, Veysel Karani District, University Street, Siirt/Türkiye.
In this study, a total of 32 Trueperella pyogenes strains isolated from different disease specimens in cattle, sheep and goats were examined. Antimicrobial susceptibility of the isolates to 10 antimicrobials were determined using the E-test method and MIC values of the antimicrobials were investigated. The genes that play a role in the antimicrobial resistance or virulence of T.
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