The National Cancer Institute (NCI) sponsored a 2-day workshop, "Next Steps in Studying the Human Microbiome and Health in Prospective Studies," in Bethesda, Maryland, May 16-17, 2017. The workshop brought together researchers in the field to discuss the challenges of conducting microbiome studies, including study design, collection and processing of samples, bioinformatics and statistical methods, publishing results, and ensuring reproducibility of published results. The presenters emphasized the great potential of microbiome research in understanding the etiology of cancer. This report summarizes the workshop and presents practical suggestions for conducting microbiome studies, from workshop presenters, moderators, and participants.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257978PMC
http://dx.doi.org/10.1186/s40168-018-0596-zDOI Listing

Publication Analysis

Top Keywords

steps studying
8
studying human
8
human microbiome
8
microbiome health
8
health prospective
8
16-17 2017
8
conducting microbiome
8
microbiome studies
8
microbiome
5
prospective studies
4

Similar Publications

Background: This study aimed to identify a set of newborn signal functions (NSFs) that can categorize health facilities and assist policymakers and health managers in appropriately planning and adequately monitoring the progress and performance of health facilities delivering newborn health care in Bangladesh and similar low-income settings.

Methods: A modified Delphi method was used to identify a set of NSFs and a cross-sectional health facility assessment among the randomly selected facilities was conducted to test them in public health facilities in Bangladesh. In the modified Delphi approach, three main steps of listing, prioritizing, and testing were followed to identify the set of NSFs.

View Article and Find Full Text PDF

Background: The Vero cell rabies vaccine is currently the most widely used human rabies vaccine. However, owing to the presence of residual host cell DNA (HCD) in the final product and the potential tumorigenicity of the DNA of high-passage Vero cells, the WHO not only sets a limit on the number of times cells used in production can be passaged, but also imposes strict requirements on the amount of residual HCD in the final vaccine product.

Objectives: To systematically reduce the HCD level in the final vaccine product, multiple purification steps are included in the vaccine production process.

View Article and Find Full Text PDF

Foot strike patterns influence vertical loading rates during running. Running retraining interventions often include switching to a new foot strike pattern. Sudden changes in the foot strike pattern may be uncomfortable and may lead to higher step-to-step variability.

View Article and Find Full Text PDF

This study investigated the relationship between stepping-defined daily activity levels, time spent in different postures, and the patterns and intensities of stepping behaviour. Using a thigh-mounted triaxial accelerometer, physical activity data from 3547 participants with seven days of valid data were analysed. We classified days based on step count and quantified posture and stepping behaviour, distinguishing between indoor, community, and recreation stepping.

View Article and Find Full Text PDF

Traditional marker-based photogrammetry systems often require the attachment and removal of a sticker for each measured point, involving labor-intensive manual steps. This paper presents an innovative approach that utilizes raised, cross-shaped markers, referred to as 'molded markers', directly embedded into composite pieces. In this study, these markers, commonly employed in other industrial processes, serve as fiducial markers for accurate photogrammetry.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!