Currently, noninvasive cost-effective techniques capable of quantifying non-uniform degradation of tendon's mechanical and structural properties associated with localized tendon injuries are not readily available. This study demonstrates the applicability of a simple surface-wave elastography (SURF-E) method for assessing the stiffness of the Achilles Tendon by measuring the propagation velocity of surface waves along the tendon in a much broader range of values than currently available Ultrasound-based or MRI-based elastography methods do. Results from this study confirm the non-uniform stiffening of the AT during passive ankle dorsiflexions.
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http://dx.doi.org/10.1016/j.jbiomech.2018.11.012 | DOI Listing |
Materials (Basel)
August 2024
Centre for Assessment of Structures and Materials under Extreme Conditions (CASMEC), Department of Mechanical and Aerospace Engineering, Brunel University London, London UB8 3PH, UK.
The aim of the work presented in this paper was development of a thermodynamically consistent constitutive model for orthotopic metals and determination of its parameters based on standard characterisation methods used in the aerospace industry. The model was derived with additive decomposition of the strain tensor and consisted of an elastic part, derived from Helmholtz free energy, Hill's thermodynamic potential, which controls evolution of plastic deformation, and damage orthotopic potential, which controls evolution of damage in material. Damage effects were incorporated using the continuum damage mechanics approach, with the effective stress and energy equivalence principle.
View Article and Find Full Text PDFEur Phys J E Soft Matter
August 2024
CNRS, FAST, Université Paris-Saclay, 91405, Orsay, France.
Shear thickening fluids are liquids that stiffen as the applied stress increases. If many of these types of fluids follow a monotonic rheological curve, some experimental and numerical studies suggest that certain fluids, like cornstarch, may exhibit a non-monotonic, S-shaped rheology. Such non-monotonic behavior has however proved very difficult to observe experimentally in classical rheometer.
View Article and Find Full Text PDFBiomech Model Mechanobiol
December 2023
Department of Pediatrics (Cardiology), Stanford University, Stanford, CA, 94305, USA.
Hemodynamic loading is known to contribute to the development and progression of pulmonary arterial hypertension (PAH). This loading drives changes in mechanobiological stimuli that affect cellular phenotypes and lead to pulmonary vascular remodeling. Computational models have been used to simulate mechanobiological metrics of interest, such as wall shear stress, at single time points for PAH patients.
View Article and Find Full Text PDFbioRxiv
April 2023
Department of Pediatrics (Cardiology), Stanford University.
Hemodynamic loading is known to contribute to the development and progression of pulmonary arterial hypertension (PAH). This loading drives changes in mechanobiological stimuli that affect cellular phenotypes and lead to pulmonary vascular remodeling. Computational models have been used to simulate mechanobiological metrics of interest, such as wall shear stress, at single time points for PAH patients.
View Article and Find Full Text PDFFront Netw Physiol
February 2023
Department of Biomedical Engineering, Boston University, Boston, MA, United States.
Pulmonary Fibrosis (PF) is a deadly disease that has limited treatment options and is caused by excessive deposition and cross-linking of collagen leading to stiffening of the lung parenchyma. The link between lung structure and function in PF remains poorly understood, although its spatially heterogeneous nature has important implications for alveolar ventilation. Computational models of lung parenchyma utilize uniform arrays of space-filling shapes to represent individual alveoli, but have inherent anisotropy, whereas actual lung tissue is isotropic on average.
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