AI Article Synopsis

  • Gram-negative bacteria in the mouth can be problematic for chemotherapy patients.
  • A study tested the effectiveness of 0.12% chlorhexidine mouthwash compared to a placebo in these patients.
  • Results showed no significant difference in bacterial levels, suggesting that local factors might affect how well chlorhexidine works.

Article Abstract

The presence of gram-negative bacteria in the oral cavity is an undesirable occurrence in patients undergoing chemotherapy. Our aim was to investigate the antibacterial effect of 0.12% chlorhexidine mouthwash in chemotherapypatients with a randomized, double-blind, placebo-controlled trial. There were no significant differences between oral colonization rates; there may be local factors that interfere with chlorhexidine activity.

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http://dx.doi.org/10.1016/j.ajic.2018.09.005DOI Listing

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