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Giant Cell Myocarditis vs Cardiac Sarcoidosis: Reconsidering the Diagnosis With FDG PET Imaging.
JACC Case Rep
November 2024
MedStar Heart and Vascular Institute, Washington, DC, USA.
Article Synopsis
- Giant cell myocarditis (GCM) and cardiac sarcoidosis have similar symptoms and tissue characteristics, leading to questions about their relationship on the inflammatory cardiomyopathy spectrum.
- The case involves a patient who experienced cardiogenic shock linked to GCM, confirmed by biopsy.
- After a heart transplant, the patient was diagnosed with sarcoidosis using 18-fluorodeoxyglucose PET imaging and another biopsy.
Insights into the paradoxical effect of smoking on vasculitis: a comprehensive review.
Sarcoidosis Vasc Diffuse Lung Dis
December 2024
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Vasculitis is a group of uncommon diseases characterized by inflammation of blood vessels, which contributes to the organ ischemia and damage. Cigarette smoke contains a high concentration of various toxins, which have the potential to affect the immune response and development of autoimmune/autoinflammatory rheumatic diseases including vasculitis. Smoking influences both innate and adaptive immune systems and plays binary functions in modulating immunity by either aggravating pathogenic immune responses or attenuating defensive immunity.
View Article and Find Full Text PDFEar, Nose, and Throat sarcoidosis: An etiology that should raise a flag? About two case reports.
Tunis Med
November 2024
Department of Internal Medicine, Rabta University Hospital Center, Tunisia.
Introduction: Sarcoidosis is a chronic inflammatory disease characterized by non-caseous necrotizing epithelial cell granulomas that can affect any organ. Ear, nose, and throat (ENT) involvement is rare. We report two cases of systemic sarcoidosis with ENT onset.
View Article and Find Full Text PDFCardiovascular outcomes among giant cell myocarditis compared with cardiac sarcoidosis: A propensity score-matched analysis.
Prog Cardiovasc Dis
November 2024
Division of Cardiovascular Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address:
Background: Giant cell myocarditis (GCM) and cardiac sarcoidosis (CS) are rare inflammatory diseases of the myocardium with poor prognosis. Cardiovascular disease outcomes among both diseases have not been well studied with limited literature.
Objective: This study aims to investigate the cardiovascular outcomes among patients with GCM and CS.
Histopathological Evaluation of Somatostatin Receptor 2 Expression in Myocarditis-Rationale for the Diagnostic Use of Somatostatin Receptor Imaging.
Diagnostics (Basel)
October 2024
Department of Clinical Pathology, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.
Background/objectives: Myocarditis is an inflammatory disease of the myocardium and remains to this day a challenging diagnosis. A promising novel imaging method uses the expression of somatostatin receptors (SSTRs) on inflammatory cells to visualize myocardial inflammation. However, little is known about the histopathological correlate of SSTR imaging in different forms of myocarditis.
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