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How Much Data Are Enough? Toward Statistically Robust Adhesion Experiments by Atomic Force Microscopy.
Langmuir
January 2025
Department of Physical Chemistry II, University of Bayreuth, Universitaetsstrasse 30, Bayreuth 95447, Germany.
Direct force measurements by atomic force microscopy (AFM) have become an indispensable analytical tool in the last decades. Force measurements have been widely used for adhesion measurements, often in combination with the colloidal probe technique. For the latter technique, a colloidal particle is attached to the end of an AFM cantilever, proving great flexibility in terms of colloid/surface interaction to be studied.
View Article and Find Full Text PDFDevelopment and implementation of an electronic health record system for use in humanitarian emergencies, disaster response, and conflict zones.
PLOS Glob Public Health
January 2025
Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Humanitarian medical response to natural and human-made disasters can be complicated by high clinician, staff, and patient turnover. While electronic medical records are being scaled up globally, their use remains limited in humanitarian response settings. The Fast Electronic Medical Record (fEMR) system is an open-source electronic health record system specifically designed for use in resource-limited settings and humanitarian crises.
View Article and Find Full Text PDFPrognostic significance and accuracy of oncologists' estimates of survival time in recurrent ovarian cancer.
Int J Gynecol Cancer
January 2025
The NHMRC Clinical Trials Centre, The University of Sydney, Sydney, NSW, Australia; Macarthur Cancer Therapy Centre, Sydney, NSW, Australia; Western Sydney University, Department of Medicine, Sydney, NSW, Australia. Electronic address:
Objective: We evaluated the accuracy of oncologists' estimates of expected survival time in recurrent ovarian cancer.
Methods: Oncologists estimated expected survival time at baseline for each patient, who were then followed up for survival time. We hypothesized that oncologists' estimates of expected survival time would be independently significant predictors of survival, unbiased (approximately equal proportions [50%] living longer versus shorter than their expected survival time), or imprecise (<30% within 0.
Genomic Footprints of Hybridisation in North Atlantic Eels (Anguilla anguilla and A. rostrata).
Mol Ecol
January 2025
Department of Biology, Aarhus University, Aarhus C, Denmark.
Understanding interspecific introgressive hybridisation and the biological significance of introgressed variation remains an important goal in population genomics. European (Anguilla anguilla) and American eel (A. rostrata) represent a remarkable case of hybridisation.
View Article and Find Full Text PDFTime-varying reproduction number estimation: fusing compartmental models with generalized additive models.
J R Soc Interface
January 2025
Department of Mathematics, The University of Manchester, Manchester, UK.
The reproduction number, the mean number of secondary cases infected by each primary case, gives an indication of the effort required to control the disease. Beyond the well-known reproduction number, there are two natural extensions, namely the and reproduction numbers. As behaviour, population immunity and viral characteristics can change with time, these reproduction numbers can vary over time.
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