In order to understand infection of avian influenza A virus (AIV) and canine distemper virus (CDV) in the Siberian Tiger in Northeast China, 75 Siberian Tiger serum samples from three cap- tive facilities in northeastern China were collected. AIV and CDV antibody surveillance was test- ed by using hemagglutination inhibition and serum neutralization methods. The results showed that the seroprevalence of H5 AIV, H9 AIV and CDV was respectively 9.33% (7/75), 61.33% (46/75) and 16% (12/75). In the 1⟨years ⟨2 and > 5 year-old group, the seroprevalence of the H9 AIV was 24% and 80% (P ⟨ 0.01), and the CDV seroprevalence was 6% and 36% (P ⟨ 0.01), respectively. It was demonstrated that 3 (4%) out of 75 serum samples were AIV+CDV seropos- itive, with 2.67% (2/75) in H9+AIV and 1.33% (1/75) in H5+H9+AIV. To our knowledge, this is the first report of AIV and CDV seroprevalence in Siberian Tigers in China, which will provide base-line data for the control of AIV and CDV infection in Siberian Tigers in China.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.24425/122621 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Serological surveillance of avian influenza virus and canine distemper virus in captive Siberian Tigers in Northeastern China.
Pol J Vet Sci
September 2018
College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, P. R. China.
In order to understand infection of avian influenza A virus (AIV) and canine distemper virus (CDV) in the Siberian Tiger in Northeast China, 75 Siberian Tiger serum samples from three cap- tive facilities in northeastern China were collected. AIV and CDV antibody surveillance was test- ed by using hemagglutination inhibition and serum neutralization methods. The results showed that the seroprevalence of H5 AIV, H9 AIV and CDV was respectively 9.
View Article and Find Full Text PDFMolecular cloning and functional characterization of eleven subtypes of interferon-α in Amur tigers (Panthera tigris altaica).
Dev Comp Immunol
December 2017
Department of Physiology, College of Wildlife Resources, Northeast Forestry University, Harbin 150040, Heilongjiang, PR China. Electronic address:
Interferon has a broad-spectrum of antiviral effects and represents an ideal choice for the development of antiviral drugs. Nonetheless, information about alpha interferon (IFN-α) is vacant in Amur tiger (Panthera tigris altaica), an endangered species and indigenous to northeast Asia. Herein, 11 PtIFN-αs genes, which encoded proteins of 164-165 amino acids, were amplified.
View Article and Find Full Text PDF[Comparison of antiviral activity between FeIFN-omega and FeIFN-alpha].
Sheng Wu Gong Cheng Xue Bao
September 2008
College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, China.
Both IFN-omega and IFN-alpha belong to type I interferon and have antiviral, antiproliferative, immunomodulatory activities, but their bioactivities are usually different. FeIFN-omega gene was amplified by PCR. FeIFN-alpha gene was synthesized based on the published sequences of GenBank.
View Article and Find Full Text PDFMicropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier.
Cancer Res
October 1992
Nuclear Medicine Department, National Cancer Institute, NIH, Bethesda, Maryland 20892.
Monoclonal antibodies (MAbs) often distribute nonuniformly in tumors. In part, that observation reflects intrinsic heterogeneity within the tumor; in part, it reflects poor penetration through tumor substance. Several years ago, we proposed the "binding site barrier" hypothesis (J.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!