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A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds.
Sci Rep
November 2024
Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Coronary artery disease (CAD) is characterized by narrowing and subsequent blockade of coronary arteries, and imposes a significant health and economic burden. Stent and scaffold devices are introduced in advanced CAD to improve vascular stability and restore blood flow. Although in vitro flow systems like the Chandler loop have been developed to enhance the understanding of interactions between device materials, their coatings, and vascular cells, imaging-based in vitro analysis of device performance is limited.
View Article and Find Full Text PDFVery late Magmaris scaffold restenosis: a 6-year serial optical coherence tomography case report.
Eur Heart J Case Rep
July 2024
Department of Cardiology, Odense University Hospital, Odense, Denmark.
Background: Bioresorbable scaffolds (BRS) have been proposed as an alternative to drug-eluting stents (DES), offering radial support during the early phases of healing, while potentially reducing the risk of long-term complications. A magnesium-based BRS (MgBRS) has shown promising results after implantation. However, there is a lack of knowledge regarding the long-term outcomes.
View Article and Find Full Text PDFTwo-Year Outcomes for Patients with Non-ST-Elevation Acute Coronary Syndrome Treated with Magmaris and Absorb Bioresorbable Scaffolds in Large-Vessel Lesions.
J Pers Med
May 2024
1st Department of Cardiology, Poznan University of Medical Sciences, 61-491 Poznan, Poland.
Background: The acute coronary syndrome (ACS) continues to be a fundamental indication for revascularization by percutaneous coronary intervention (PCI). Drug-eluting stent (DES) implantation remains a part of contemporary practice but permanent caging of the vascular structure with the metallic stent structure may increase the rate of device-related adverse clinical events. As an alternative to classic metallic DESs, the bioresorbable scaffolds (BRSs) have emerged as a temporary vascular support technology.
View Article and Find Full Text PDFMagnesium bioresorbable scaffold (Magmaris) versus polymer biodegradable ultrathin drug-eluting stent (Ultimaster) in acute coronary syndrome. Mid-term outcomes (2 years).
Postepy Kardiol Interwencyjnej
March 2024
1 Department of Cardiology, University of Medical Sciences, Poznan, Poland.
Introduction: Acute coronary syndrome (ACS) is a well-known risk factor for adverse clinical outcomes in percutaneous coronary intervention (PCI). Therefore, evaluation of coronary stents in this challenging clinical scenario can provide unique information on device safety and efficacy. Bioresorbable scaffolds (BRS) were designed to overcome long-term complications related to permanent vessel caging with a permanent metallic drug-eluting stent (DES).
View Article and Find Full Text PDFOptimal lesion preparation before implantation of a Magmaris bioresorbable scaffold in patients with coronary artery stenosis: Rationale, design and methodology of the OPTIMIS study.
Contemp Clin Trials Commun
April 2024
Department of Cardiology, Odense University Hospital, Odense, Denmark.
Article Synopsis
- * Eighty-two patients were randomly assigned to receive either a non-compliant scoring balloon or a standard non-compliant balloon for pre-dilatation before the MgBRS implantation, with evaluations conducted using advanced imaging techniques at 6 and 12 months.
- * The researchers hypothesized that using a non-compliant scoring balloon would lead to better outcomes in lumen preservation compared to a standard balloon, with results to be assessed based on lumen dimensions over the follow-up period.
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