Downregulation of emotional responses to threat is strongly associated with frontal cortex functions. Additionally pathological anxiety has been proposed to be associated with the altered frontal control. Understanding the frontal regulation of both initial and sustained fear responses seems to be crucial for further research on the treatment of anxiety disorders. Therefore, this study aims to examine the effects of transcranial direct current stimulation (tDCS) over the right inferior frontal cortex (rIFC) on the subjects' psychophysiological responses as measured by skin conductance reaction (SCR) during a sustained threat paradigm. 80 participants were randomly assigned to an anodal and sham stimulation group in a double-blinded manner. Indicated by visual cues, participants anticipated the temporally unpredictable occurrence of aversive or neutral auditory stimuli. We found a significant interaction effect of condition x tDCS for SCR during the sustained threat. Post-hoc tests revealed a significant reduction in SCR during sustained fear in verum stimulated group. The results confirm that tDCS of the rIFC attenuates sustained fear. This supports the suggested role of the rIFC in psychophysiological emotional regulation and the potential use of tDCS to enhance these effects.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.biopsycho.2018.10.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Post-traumatic stress disorder (PTSD) symptom clusters associated with an indicator of heart rate variability: The ADVANCE cohort study.
J Affect Disord
January 2025
King's Centre for Military Health Research, King's College London, SE5 9RJ, United Kingdom of Great Britain and Northern Ireland; Academic Department of Military Mental Health, King's College London, SE5 9RJ, United Kingdom of Great Britain and Northern Ireland.
Background: Heart rate variability (HRV) is governed by sympathetic and parasympathetic regulatory systems. Post-Traumatic Stress Disorder (PTSD) may influence these systems and consequently affect cardiovascular functioning.
Methods: The sample consisted of 860 UK male military personnel approximately half of whom had sustained physical combat injuries in Afghanistan.
BARRIERS AND ENABLERS OF DIETARY REINTRODUCTION FOLLOWING NEGATIVE ORAL FOOD CHALLENGE: A SCOPING REVIEW.
J Allergy Clin Immunol Pract
January 2025
University of Queensland, St Lucia, Australia; Centre for Food Allergy Research, Murdoch Children's Research Institute, Parkville, Australia. Electronic address:
Background: Following a negative oral food challenge (OFC), it is recommended the individual continues to consume the historical allergen regularly. However, the proportion of families achieving sustained reintroduction, and enablers and barriers for reintroduction, are currently unclear.
Objective: To understand the frequency and definitions of optimal food reintroduction in children and adolescents following negative OFC, and associated barriers and enablers.
Social network sites (SNS) an archetype of techno-social stress: A systematic review.
Heliyon
January 2025
Department of Information Technology, De La Salle University, Philippines.
Background: Social Networking Sites (SNS) are widely used platforms known for both their hedonic and social connectivity benefits. Although there is considerable interest in understanding how personal technostress affects individual well-being, a significant gap remains in the systematic exploration of this topic within the literature.
Methods: This review systematically examined 41 empirical studies from Scopus and PubMed published between 2014 and 2023, following PRISMA guidelines, and assessed for methodological quality using the Mixed Method Appraisal Tool.
The prevalence of mental health issues among nursing students: An umbrella review synthesis of meta-analytic evidence.
Int J Nurs Stud
January 2025
Research Laboratory Psychology of Patients, Families & Health Professionals, Department of Nursing, School of Health Sciences, University of Ioannina, Ioannina 45500, Greece. Electronic address:
Background: The ongoing global student mental health crisis indicates the urgent need for updated research specifically targeting nursing students. Considering their anticipated transition into healthcare professions, their mental well-being is critical, not only for their academic performance but also for the quality of care they will deliver in their professional roles.
Objective: To estimate the prevalence of mental health issues among nursing students by synthesizing data from systematic reviews and meta-analyses.
High-Intensity Training Telerehabilitation for Persons with Chronic Low Back Pain: A Pilot Clinical Trial.
J Clin Med
December 2024
REVAL Rehabilitation Research Center, University of Hasselt, 3500 Hasselt, Belgium.
High-intensity training (HIT) has been shown to enhance physical fitness and reduce functional impairments in persons with moderately disabling chronic nonspecific low back pain (CNSLBP). However, sustaining these improvements post-rehabilitation remains a challenge. To address this, a home-based, technology-supported HIT program utilizing telerehabilitation can be implemented at home.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!