Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/00026980.2016.1227175 | DOI Listing |
Med
December 2024
BioMarin (UK) Limited, Ltd., London, UK.
Background: Vosoritide is a C-type natriuretic peptide analog that addresses an underlying pathway causing reduced bone growth in achondroplasia. Understanding the vosoritide treatment effect requires evaluation over an extended duration and comparison with outcomes in untreated children.
Methods: After completing ≥6 months of a baseline observational growth study and 52 weeks in a double-blind, placebo-controlled study (ClinicalTrials.
Water Res
December 2024
Soil Chemistry and Chemical Soil Quality Group, Wageningen University & Research, PO BOX 47, Wageningen 6700 AA, the Netherlands.
Binding of glyphosate (PMG) to metal (hydr)oxides controls its availability and mobility in natural waters and soils, and these minerals are often suggested for the removal of PMG from wastewaters. However, a solid mechanistic and quantitative description of the adsorption behavior and surface speciation on these surfaces is still lacking, while it is essential for understanding PMG behavior in aquatic and terrestrial systems. This study gives new insights through advanced surface complexation modeling of new and previously published adsorption data, supplemented with MO/DFT calculations of the geometry, thermochemistry and theoretical infrared (IR) spectra of the surface complexes.
View Article and Find Full Text PDFPLoS One
December 2024
Faculty of Economics and Management, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
In this paper, we investigate how technology has contributed to experimental economics in the past and illustrate how experimental economics can contribute to technological progress in the future. We argue that with machine learning (ML), a new technology is at hand, where for the first time experimental economics can contribute to enabling substantial improvement of technology. At the same time, ML opens up new questions for experimental research because it can generate previously impossible observations.
View Article and Find Full Text PDFHistochem Cell Biol
December 2024
Institute of Pathology, Klinikum Bayreuth, 95445, Bayreuth, Germany.
A20, an ubiquitin-editing enzyme, plays a pivotal role in regulating cell signaling and immune responses. Dysregulated A20 expression has been associated with various pathological conditions, including inflammatory diseases and malignancies, where its expression levels often correlate with differing prognoses in solid tumors. This study aimed to explore the expression and cellular localization of A20 in both nonpathological and diseased human gastric tissues to gain deeper insights into its involvement in gastric pathologies.
View Article and Find Full Text PDFFront Neurosci
December 2024
Institute of Physiology, RG Neurophysiology and Optogenetics, Medical Faculty, Otto-von-Guericke-University, Magdeburg, Germany.
Cognitive function in healthy aging and neurodegenerative diseases like Alzheimer's disease (AD) correlates to olfactory performance. Aging and disease progression both show marked olfactory deficits in humans and rodents. As a clear understanding of what causes olfactory deficits is still missing, research on this topic is paramount to diagnostics and early intervention therapy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!