Radio-Frequency Safety Assessment of Stents in Blood Vessels During Magnetic Resonance Imaging.

Front Physiol

Division of Biomedical Physics, Office of Science and Engineering Laboratory, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD, United States.

Published: October 2018

The purpose of this study was to investigate the need for high-resolution detailed anatomical modeling to correctly estimate radio-frequency (RF) safety during magnetic resonance imaging (MRI). RF-induced heating near metallic implanted devices depends on the electric field tangential to the device ( ). and specific absorption rate (SAR) were analyzed in blood vessels of an anatomical model to understand if a standard gel phantom accurately represents the potential heating in tissues due to passive vascular implants such as stents. A numerical model of an RF birdcage body coil and an anatomically realistic virtual patient with a native spatial resolution of 1 mm were used to simulate the electric field at 64 MHz (1.5 T MRI system). Maximum values of SAR inside the blood vessels were calculated and compared with peaks in a numerical model of the ASTM gel phantom to see if the results from the simplified and homogeneous gel phantom were comparable to the results from the anatomical model. values were also calculated in selected stent trajectories inside blood vessels and compared with the ASTM result. Peak SAR values in blood vessels were up to ten times higher than those found in the ASTM standard gel phantom. Peaks were found in clinically significant anatomical locations, where stents are implanted as per intended use. Furthermore, results showed that volume-averaged SAR values might not be sufficient to assess RF safety. Computational modeling with a high-resolution anatomical model indicated higher values of the incident electric field compared to the standard testing approach. Further investigation will help develop a robust safety testing method which reflects clinically realistic conditions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232906PMC
http://dx.doi.org/10.3389/fphys.2018.01439DOI Listing

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