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Daylight Photodynamic Therapy: At-Home Delivery.
J Clin Med
December 2024
School of Medicine, University of Dundee, Dundee DD1 4HN, UK.
This pilot study evaluated the design, usability, and practicality of the dPDT@home kit for treating actinic keratoses (AKs) on the face and scalp. The kit allowed patients to manage their treatment at home, reducing hospital visits and utilizing natural sunlight. While patients were very willing to use the kit again, further studies are required to evaluate outcomes and ascertain the need for additional improvements and support.
View Article and Find Full Text PDFIs the benefit of sequential 5-fluorouracil and daylight photodynamic therapy versus daylight photodynamic therapy alone sustained over time? - 12-month follow-up of a randomized controlled trial.
Photodiagnosis Photodyn Ther
December 2024
Department of Dermatology, Copenhagen University Hospital Bispebjerg, Nielsine Nielsens Vej 9, 2400 Copenhagen NV, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen NV, Denmark.
Background: Since recurrences and new AKs commonly are observed after treatment long-term effects of field-directed therapies for AKs are crucial. Thus, we evaluated the 6- and 12-month efficacy and satisfaction of sequential topical 5-fluorouracil (5-FU) and daylight PDT (dPDT) with dPDT alone.
Methods: In a randomized intra-individual study patients with multiple AKs in the face and scalp were treated with 4 % 5-fluorouracil cream twice daily for 7 days on one side of the scalp/face, followed by dPDT on both sides.
Vascular Characteristics of Treatment-resistant and -responsive Actinic Keratosis Identified with Dynamic Optical Coherence Tomography.
Acta Derm Venereol
November 2024
Department of Dermatology, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Treatment-resistant actinic keratosis (AK) is of concern in clinical practice, often requiring retreatment. Microvascular assessments might help differentiate treatment-resistant from treatment-responsive AKs, enabling targeted treatment. Using dynamic optical coherence tomography, AK vascularization was investigated following daylight photodynamic therapy, comparing treatment-resistant with cleared AKs.
View Article and Find Full Text PDFA Case Report on the Successful Use of Daylight Photodynamic Therapy With BF-200 ALA Combined With Topical Terbinafine for the Treatment of Tinea Capitis Caused by Trichophyton rubrum in a Patient With Autoimmune Chronic Hepatitis.
Photodermatol Photoimmunol Photomed
November 2024
Department of Dermatology, Hospital Regional Universitario de Málaga, Málaga, Spain.
Photodynamic Therapy in Acne Vulgaris: A Systematic Review.
J Cutan Med Surg
November 2024
Toronto Dermatology Centre, Toronto, ON, Canada.
Acne is a multifactorial disorder of the pilosebaceous unit. Photodynamic therapy (PDT) is an energy-based treatment shown to be safe in acne vulgaris, although the mechanism of action of PDT in acne is incompletely understood. This review summarizes the clinical features of and treatment efficacy in acne patients treated with PDT.
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