Prediction of sensory texture attributes using instrumental measurements is a very important challenge for cosmetic industry because in vivo sensory studies are expensive, time consuming and limited by the safety issue of applied products. The aim of this work is to investigate how residual sensory properties of cosmetic products can be predicted without using a panel of assessors, focusing on the residual film attribute "Stickiness". 10 cosmetic products with different galenics have been selected and evaluated in vivo using a classical sensory protocol, developed according to the Spectrum Descriptive Analysis method. In addition to this study, products were evaluated after their application on non-biological skin models in order to compare perceptions onto in vivo skin and artificial surfaces. Results obtained show that in vivo perceptions can be compared with the ones on artificial surfaces meaning that residual film stickiness is similar between in vivo skin and non-biological skin models. An instrumental protocol using a texture analyzer has been set up to evaluate residual film adhesiveness. This protocol has been tested and validated in vivo (r² = 0.90; RPD = 3.07) before being optimized on a selected non-biological skin model Bioskin® (Beaulax, Co. Ltd. Tokyo, Japan) owning good correlation with in vivo perceptions. Established model shows excellent predictive ability with a r² of 0.94 and a RPD of 3.38, as highlighted by the 4 steps cross-validation performed. It proves that physical stimulus responsible for cosmetic film stickiness can be instrumentally measured on both in vivo skin and artificial skin.
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http://dx.doi.org/10.1016/j.colsurfb.2018.10.062 | DOI Listing |
ACS Nano
January 2025
State Key Laboratory of Wide-Bandgap Semiconductor Devices and Integrated Technology, Faculty of Integrated Circuit, Xidian University, 710071 Xi'an, China.
Flexible perovskite solar cells (FPSCs) have advanced significantly because of their excellent power-per-weight performance and affordable manufacturing costs. The unsatisfactory efficiency and mechanical stability of FPSCs are bottleneck challenges that limit their application. Here, we explore the use of octylammonium acetate (OAAc) with a long, intrinsic, flexible molecular chain on perovskite films for surface adhesion and mechanical releasing.
View Article and Find Full Text PDFThe current research discusses polymer conjugation, formulation development, and evaluation of sorafenib-loaded polymeric nanomicelles of conjugated soluplus (solu-tin) and polymeric mixed nanomicelles of conjugated soluplus (solu-tin) with conjugated poloxamer 188 (polo-tin) for site-specific posterior segment delivery to the retina in managing retinoblastoma. Firstly, the soluplus and poloxamer 188 were conjugated with biotin by Fischer esterification reaction and evaluated by FTIR and H NMR for confirmation of covalent bond formation involving the carboxyl group of biotin and hydroxyl group of polymers. Secondly, the sorafenib-loaded solu-tin nanomicelles and mixed nanomicelles of solu-tin with polo-tin were formulated by the thin film hydration method.
View Article and Find Full Text PDFBiomaterials
January 2025
Department of Ultrasound, Southwest Hospital, Army Medical University, Chongqing, 400038, China. Electronic address:
Chemotherapy combined with immunotherapy is a highly promising approach for treating tumors. However, chemotherapeutic drugs often fail to accumulate effectively at the tumor site after systemic administration and they lack sufficient immunogenicity to activate adaptive immunity, making an effective T-cell immune response within the tumor microenvironment difficult to achieve. Here, this work developed drug-loaded nanobubbles (DTX-R837@NBs) that encapsulate the chemotherapy drug docetaxel and the immune adjuvant R837 via a thin-film hydration method.
View Article and Find Full Text PDFMicrosc Microanal
January 2025
Université de Lorraine, CNRS, Arts et Métiers, LEM3, Metz 57070, France.
Characterizing threading dislocations (TDs) in gallium nitride (GaN) semiconductors is crucial for ensuring the reliability of semiconductor devices. The current research addresses this issue by combining two techniques using a scanning electron microscope, namely electron channeling contrast imaging (ECCI) and high-resolution electron backscattered diffraction (HR-EBSD). It is a comparative study of these techniques to underscore how they perform in the evaluation of TD densities in GaN epitaxial layers.
View Article and Find Full Text PDFMolecules
December 2024
School of Advanced Materials and Nanotechnology, Xidian University, Xi'an 710126, China.
The advancement of miniaturizing electronic information technology draws growing interest in dielectric capacitors due to their high-power density and rapid charge/discharge capabilities. The sol-gel method was utilized to fabricate the 0.75Pb(ZrTi)O-0.
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