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Presenting predictions and performance of probabilistic models for clinical decision support in trauma care.
Int J Med Inform
February 2025
Department of Cognitive Science, Graduate School of Informatics, Middle East Technical University, Turkey. Electronic address:
Introduction: Both predictions and performance of clinical predictive models can be presented with various verbal and visual representations. This study aims to investigate how different risk and performance presentations for probabilistic predictions affect clinical users' judgement and preferences.
Methods: We use a clinical Bayesian Network (BN) model that has been developed for predicting the risk of Trauma Induced Coagulopathy (TIC).
Air pollution mixture exposure during pregnancy and postpartum psychological functioning: racial/ethnic- and fetal sex-specific associations.
J Expo Sci Environ Epidemiol
November 2024
Department of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Background: Prenatal air pollution (AP) exposure has been linked to postpartum psychological functioning, impacting health outcomes in both women and children. Extant studies primarily focused on individual pollutants.
Objective: To assess the association between prenatal exposure to a mixture of seven AP components and postpartum psychological functioning using daily exposure data and data-driven statistical methods.
Background: Borderline personality disorder (BPD) is a debilitating psychiatric illness whose symptoms frequently emerge during adolescence. Initial studies in adults suggest that the interpersonal difficulties common in BPD may emerge from disrupted processing of social and emotional stimuli. Less is known about these processes in adolescents with BPD symptoms, despite substantial changes in socioemotional processing during this developmental period.
View Article and Find Full Text PDFBody fatness across the adult life course and ovarian cancer risk.
Eur J Epidemiol
October 2024
Department of Oncology, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Article Synopsis
- Excess body fat in older age can increase the risk of ovarian cancer, although the connection is not very strong.
- A study in Montreal analyzed body mass index (BMI) data over decades for women 50 and older to understand different life stages' impact on ovarian cancer risk.
- The findings indicate that the accumulation hypothesis best explains the link between BMI and ovarian cancer risk, particularly highlighting the early childbearing years as a potentially sensitive period for increased risk.
Neoadjuvant therapy versus upfront surgery in resectable pancreatic cancer: reconstructed patient-level meta-analysis of randomized clinical trials.
BJS Open
September 2024
HPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, University of Navarra, Pamplona, Spain.
Background: Neoadjuvant treatment has shown promising results in patients with borderline resectable pancreatic ductal adenocarcinoma. The potential benefits of neoadjuvant treatment on long-term overall survival in patients with resectable pancreatic ductal adenocarcinoma have not yet been established. The aim of this study was to compare long-term overall survival of patients with resectable pancreatic ductal adenocarcinoma based on whether they received neoadjuvant treatment or underwent upfront surgery.
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