AI Article Synopsis
- Small-scale farming can significantly influence the spread of antibiotic resistance in humans.
- Observations from rural northwestern Esmeraldas, Ecuador, revealed a concerning 66.1% resistance to cefotaxime (CTX) among farmed broiler chickens.
- The study detected rising CTX resistance levels in backyard chickens not given antibiotics, and identified identical bacterial sequences in both humans and chickens, indicating a potential transfer of resistance.
- These results underscore how local meat production practices directly affect antibiotic resistance in vulnerable communities.
Article Abstract
Small-scale farming may have large impacts on the selection and spread of antimicrobial resistance to humans. We conducted an observational study to evaluate antibiotic-resistant populations from poultry and humans in rural northwestern Esmeraldas, Ecuador. Our study site is a remote region with historically low resistance levels of third-generation antibiotics such cefotaxime (CTX), a clinically relevant antibiotic, in both poultry and humans. Our study revealed 1) high CTX resistance (66.1%) in farmed broiler chickens, 2) an increase in CTX resistance over time in backyard chicken not fed antibiotics (2.3-17.9%), and 3) identical sequences from human and chicken bacteria, suggesting a spillover event. These findings provide evidence that small-scale meat production operations have direct impacts on the spread and selection of clinically important antibiotics among underdeveloped settings.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367627 | PMC |
| http://dx.doi.org/10.4269/ajtmh.18-0173 | DOI Listing |
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