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Few neonatal cases of soft tissue and osteoarticular infections with have been reported. We report a rare clinical presentation of necrotizing fasciitis of the foot caused by in a 17-day-old male neonate with hypoplastic left-sided heart syndrome. Fulminant progressive black skin necrosis was triggered by fresh frozen plasma leakage from the peripheral venous access.

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An Autopsy Case of Rapidly Fulminant Group A Streptococcus Infection in a Previously Healthy 67-Year-Old Woman.

Cureus

November 2024

Department of Diagnostic Pathology (DDP) and Research Center of Diagnostic Pathology (RC-DiP), Gifu Municipal Hospital, Gifu, JPN.

, also known as group A (GAS), is responsible for various conditions, such as pharyngitis, tonsillitis, necrotizing fasciitis, and streptococcal toxic shock syndrome (STSS). STSS, a rapidly progressing infection involving shock and multi-organ failure, was first reported in Japan in 1992, and since then, the number of cases has been steadily increasing. We herein report an autopsy case of STSS that resulted in sudden death.

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The poison ivy does not normally occur in Slovakia, like in the Czech Republic, but it can be introduced. The venom of the black widow spider is an effective weapon for capturing prey. It is a mixture of various active substances containing a protein neurotoxin called α-latrotoxin (α-LTX).

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Article Synopsis
  • - Necrotizing fasciitis is a serious and often deadly infection that usually involves multiple types of bacteria, needing flexible and complex treatment, particularly when it occurs on the face, which is less common but very severe.
  • - A case study describes a patient with various health issues who developed rapid facial necrosis after nasal trauma, leading to critical health decline and complicated treatment, involving multiple surgeries from different specialists.
  • - Early recognition and a collaborative approach are crucial for managing facial necrotizing fasciitis effectively, aiming to save lives and reduce lasting physical and cosmetic damage.
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Article Synopsis
  • * The clinical case highlights successful treatment of a patient with significant pre-existing health issues, using local negative pressure therapy (NPWT) early in the infection process.
  • * After initial treatment, the NPWT system continued to be used to manage the wound and prepare it for closure effectively.
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