AI Article Synopsis
- A new furanone called volvafuranone A was discovered in the fruiting body of a specific mushroom, along with twelve other known compounds.
- Some of these isolated compounds were identified from the mushroom for the first time.
- The compounds were tested for their toxicity against four human tumor lines, showing significant cytotoxic effects with varying IC values.
Article Abstract
Phytochemical investigation of the fruiting body of led to the isolation of a new furanone, 2(5)-furanone-4-propionic acid named volvafuranone A (), together with twelve known compounds (). Compounds , were isolated from this mushroom for the first time. The isolated compounds were assessed for their cytotoxicity against four human tumour lines (SGC-7901, PC-3M, MCF-7, HepG-2), and the results showed that compound , , , have significant cytotoxicity with IC values of 5.90 μM (HepG-2), 20.72 μM (HepG-2), 27.98 μM (PC-3M) and 23.15 μM (PC-3M), respectively.
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| http://dx.doi.org/10.1080/14786419.2018.1509324 | DOI Listing |
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