Fifteen previously undescribed 2-(2-phenylethyl)chromone dimers, along with two known analogues were isolated from Chinese agarwood (Aquilaria sinensis) by a LC-MS-guided fractionation procedure. Their structures were elucidated on the basis of spectroscopic and spectrometric data (1D and 2D NMR, IR, and HRESIMS). The isolated compounds exhibited significant inhibition of nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells with IC values in the range 0.6-37.1 μM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.phytochem.2018.11.003 | DOI Listing |
Publication Analysis
Top Keywords
2-2-phenylethylchromone dimers
8
chinese agarwood
8
agarwood aquilaria
8
aquilaria sinensis
8
lc-ms-guided isolation
4
isolation anti-inflammatory
4
anti-inflammatory 2-2-phenylethylchromone
4
dimers chinese
4
sinensis fifteen
4
fifteen undescribed
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!